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Lung Cancer in the News: 2014 PDF Print E-mail

 

 

January | February | March | April | May | June | July
| August | September | October | November | December

 

April

Week ending April 13, 2014

Menlo Park Woman Helping to Change the Stigma of Lung Cancer
New treatments are giving hope to lung cancer patients

“Molly Golbon doesn't take much for granted these days. The 39-year old married working mom of two knows life can take unexpected turns. For her, it came with a pain in her throat, tiredness, and cough that wouldn't go away.”

Initial evaluation for free Lung Cancer Screening at Flint Library April 15
“Beverly Hospital and Beverly Radiology Associates are offering a free, low-dose chest CT screening to individuals who meet the established National Comprehensive Cancer Network’s (NCCN) high-risk criteria. Persons between the ages of 50 and 74 who have smoked at least an average of one pack of cigarettes per day for twenty-years, may meet the criteria and qualify for a free screening.”

RESEARCHERS HOPE TO MAKE LUNG CANCER SCREENING A ‘TEACHABLE MOMENT’
APRIL 10, 2014 — “A Georgetown University Medical Center researcher is launching a study she hopes will provide an opportunity for health care providers to connect with long-term smokers by pairing smoking cessation counseling with lung cancer screening.”

Lung cancer detection gets boost from new procedure at UMMC
Courtesy of University of Mississippi Medical Center Division of Public Affairs

JACKSON, Mississippi – “More lung cancer patients could be saved by a new diagnostic procedure available at the University of Mississippi Medical Center that “maps” the body’s airways with GPS-like technology.”

Lactate metabolism target halts growth in lung cancer model
“Cancer cells generate energy differently than normal cells, a characteristic that helps them to survive and metastasize. A major goal in the field of cancer metabolism is to find ways to overcome this survival advantage.”

TGen identifies growth factor receptors that may prompt metastatic spread of lung cancer
PHOENIX, Ariz. — April 9, 2014 — “Two cell surface receptors might be responsible for the most common form of lung cancer spreading to other parts of the body, according to a study led by the Translational Genomics Research Institute (TGen).”

Novel ALK Inhibitor Shows Activity in Advanced NSCLC
“The new ALK inhibitor ceritinib showed strong antitumor activity in a phase I expansion study of patients with advanced non-small-cell lung cancer (NSCLC).”

Physicians’ Education Resource® Co-Program Director Honored with Lectureship Award
PLAINSBORO, N.J. — “The Bonnie J. Addario Lung Cancer Foundation (ALCF) announced today the winner of its 2014 Lectureship Award is Dr. Roy Herbst, a medical oncologist at Yale Cancer Center and distinguished co-director of the International Lung Cancer Congress (ILCC). This award annually honors luminaries in the lung cancer field working to improve and prolong the lives of those with the disease, and its eradication.”

Study tracks new lung cancer drug target
“Researchers at Vanderbilt University have identified a potential new drug target in subtypes of lung cancer that are difficult to treat.”

Former Rams player shares connection to lung cancer
“Former St. Louis Rams linebacker Chris Draft was in town March 28 to promote his foundation and bring attention to the men and women of SSM Cancer Care who work toward improving the quality of life for lung cancer patients.”

Week ending April 7, 2014

Cell Signaling Technology, Inc. Announces PD-L1 Antibody, Important to Cancer Immunotherapy Research
DANVERS, MASS. — “Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has introduced a highly specific PD-L1 rabbit monoclonal antibody (mAb).”

Dangerous Dust: Government Pushes to Improve Workplace Safety
“Workers who breathe in silica dust have twice the normal risk of lung cancer and often develop other lung-related diseases such as asthma. Yet the rules for working with this dust — generated by mining, fracking, brickwork, floor work and other types of industry — haven’t been updated since the early 1970s.”

Roche lung cancer pill gets reprieve in UK reversal
(Reuters) – “Britain's health cost watchdog NICE on Friday reversed an earlier decision to limit the use of Roche's Tarceva cancer pill on the state health service in a move the drugmaker said would help around 2,000 patients a year.”

GSK Ends Lung Cancer Immunotherapy Trial
“GlaxoSmithKline plc announced its decision to stop the MAGRIT trial, a Phase 3 trial of its MAGE-A3 cancer immunotherapeutic in non-small cell lung cancer (NSCLC) patients, after establishing that it will not be possible to identify a sub-population of gene-signature positive NSCLC patients that may benefit from the treatment.”

Lack of Insurance Coverage a Barrier to Lung Cancer Screening
Vast majority of current, former smokers willing to undergo spiral CT, Roswell Park/MUSC study finds

BUFFALO, N.Y. — “The majority of current and former smokers would welcome screenings for lung cancer if their insurance covered the spiral computed tomography (CT) scans, according to research from Roswell Park Cancer Institute (RPCI) and the Medical University of South Carolina and published online ahead of print in the journal Lung Cancer.”

Team Identifies Novel Biomarker for Head and Neck Cancer, Non-Small Cell Lung Cancer
JUPITER, FL – “A team led by a scientist from the Florida campus of The Scripps Research Institute (TSRI) has identified a new biomarker linked to better outcomes of patients with head and neck cancers and non-small cell lung cancer.”

Woman Documents One Year Of Lung Cancer Diagnosis By Taking One Photograph Every Day
“Jennifer Glass was diagnosed with lung cancer in January 2013, just four months after getting married.”

Drug fights lung cancer by taking away its ‘chaperone’ (VIDEO)
“Chaperone proteins earned their name because they help other proteins assemble, fold, stabilize and degrade in proper manner. But in cancer, they can be hijacked to maintain and promote proteins essential for tumor growth as well.”

Neuropeptide receptors could provide treatment target for chemoresistant SCLC
medwireNews: “The discovery of a novel broad spectrum neuropeptide antagonist, peptide– 1, which is related to the substance P analogue SP-G, could help develop treatments targeted at chemoresistant small-cell lung cancer (SCLC), indicate study results.”

March

Week ending March 30, 2014

Pfizer's targeted Xalkori outshines chemo in trial of untreated lung cancer patients
“Pfizer said its targeted cancer drug Xalkori trounced chemotherapy in a trial of previously untreated patients with a particular type of lung cancer. The study showed for the first time that up-front treatment with Xalkori staves off cancer growth better than other treatments in patients whose tumors test positive for ALK-gene abnormalities.”

Immunotherapy data heralds new era of lung cancer treatment
Geneva, Switzerland, 26 March 2014 – “A new era of lung cancer therapy is close to dawning, using drugs that can prevent tumour cells from evading the immune system, experts have said at the 4th European Lung Cancer Congress.”

Immune therapy continues to advance in NSCLC
HOLLYWOOD, FLA. – “The ongoing exploration of immune therapy options for non–small cell lung cancer is a particularly exciting area of lung cancer research, because "traditionally, immune therapy hasn’t worked in lung cancer," according to Dr. Leora Horn.”

Finding lung cancer early at Rideout
Catching lung cancer early is what Dr. Royce Calhoun does.

“Since January, the cardiothoracic surgeon has performed about 15 electromagnetic navigation bronchoscopy procedures — an improved way to access and biopsy lesions deep in the lung — at Rideout Memorial Hospital.”

Novartis reports lung cancer patients respond to drug in study
“Novartis said late on Wednesday that a majority of patients given a development drug against non-small cell lung cancer had responded to the treatment, according to study results published in the New England Journal of Medicine.”

New Medication Beneficial to Lung Cancer Patients
(HealthDay News) — “The ALK inhibitor ceritinib is active in non-small-cell lung cancer (NSCLC), regardless of the presence of resistance mutations in ALK, according to a study published in the March 27 issue of the New England Journal of Medicine.”

Lung Cancer Patients’ Sexual Dysfunction Needs More Attention And Treatment, Say Doctors
“The diagnosis of cancer can be devastating for an individual. Their whole life is interrupted as the cancer causes physical and psychological changes to their body.”

Oncology, patient advocacy groups petition CMS for full coverage of CT lung cancer screening
“The Lung Cancer Alliance, the Society of Thoracic Surgeons, the American College of Radiology and other medical organizations recently petitioned CMS to provide national Medicare coverage for low-dose CT lung cancer screening for patients at high risk as defined by the United States Preventive Services Task Force.”

Week ending March 23, 2014

Inherited mutated gene increases lung cancer risk in women
“Researchers at UT Southwestern Medical Center suggest that people who have an inherited mutation of a certain gene have a high chance of getting lung cancer than heavy smokers with or without the inherited mutation.”

No Reason to Travel Elsewhere: Franciscan Alliance provides all-inclusive help for lung cancer treatment
“Anyone can get lung cancer - the number one cancer killer in America.”

Climate Risks as Conclusive as Link between Smoking and Lung Cancer
U.S. scientists say the evidence linking rising levels of greenhouse gases and global warming is as strong as the link between smoking and lung cancer

“One of the world's largest and most knowledgeable scientific bodies wants to make one point very clear: Just as smoking causes cancer, so too are humanity's greenhouse gas emissions causing the planet to change, with potentially unknown and unalterable impacts.”

Investigational vaccine reduces number of tumors in mice with lung cancer
“Researchers at UC Davis have found that the investigational cancer vaccine tecemotide, when administered with the chemotherapeutic cisplatin, boosted the immune response and reduced the number of tumors in mice with lung cancer. The study also found that radiation treatments did not significantly impair the immune response. The paper was published on March 10 in the journal Cancer Immunology Research, an American Association for Cancer Research (AACR) publication.”

Medicare, many health insurers, urged to cover proven CT lung cancer screenings
“The US Preventative Services Task Force (USPSTF), in December 2013, recommended Cat Scan (CT) lung screenings of adults ages 55 to 80 who have a 30 pack-year history and currently smoke or who have quit within the past 15 years. Results of the National Lung Screening Trial (NLST), and those of other smaller, international, randomized, controlled trials, show that CT lung cancer screening significantly reduces lung cancer deaths. Screening current and former smokers with low dose CT is the only method ever proven to reduce lung cancer mortality in this high-risk population. Lung cancer remains the number one cause of cancer deaths in the U.S.”

Full Medicare Coverage Needed for CT Lung Cancer Screening
“National Medicare coverage of low-dose computed tomography (LDCT) screening for patients at high risk for lung cancer needs to be implemented, quickly, say several medical organizations, including the American College of Radiology (ACR).”

Week ending March 16, 2014

New Lafayette clinic focuses on diagnosis, early treatment of lung cancer
“The American Cancer Society estimates that there will be more than 24,000 new cancer cases in Louisiana this year. Among those cases, 3,470 will be related to lung cancer, the ACS said.”

Managing Bone Health in Advanced Lung Cancer
“The current NCCN Guidelines recommend the addition of zoledronic acid or denosumab to upfront treatment for the management of skeletal-related events (SREs) in patients with advanced lung cancer, notes Corey J. Langer, MD. The intravenous bisphosphonate zoledronic acid was the primary drug used for the management of SREs in patients with lung cancer for several years. However, in 2010 the RANK ligand inhibitor denosumab was approved for the prevention of SREs in patients with solid tumors.”

Clearing the air: Your lung cancer risk
“Peanut butter and jelly. Peas and carrots. Smoking and lung cancer. Like it or not, some things just go together. In fact, 80 to 90 per cent of lung cancer cases in the U.S. and Canada are directly attributed to smoking.”

Alberta Cancer Foundation investing $7M into four transformative cancer research programs
“Every day 43 Albertans hear the words “you have cancer”.”

Cancer Markers Are Highly Expressed Even in Healthy Tissues Around Tumors: MD Anderson Researchers
“Researchers from the University of Texas MD Anderson Cancer Center found that cancer markers are richly expressed from the gene in the area adjacent to tumors in patients with non-small cell lung cancer (NSCLC). They also discovered a new role of a cancer-promoting gene in the lungs and airways of smokers with lung cancer. The study was published online in the Journal of the National Cancer Institute.”

Parkridge Health System Offers Low-Dose CT Lung Cancer Screening
“Parkridge Medical Center and Parkridge East Hospital now offer a $50 low-dose computed tomography (CT) lung screening recommended by the American Cancer Society for older smokers, a population that is especially at risk for developing lung cancer.”

Potential new drug targets for aggressive form of lung cancer
“Small cell lung cancer is an aggressive, highly lethal form of the disease that is linked with tobacco use. Researchers have now found mutations and other genetic interruptions occurring in the cancer's development that could translate to potential new drug targets for this disease.”

Week ending March 9, 2014

Centers for Medicare & Medicaid Services (CMS) takes first steps to cover lung cancer screening – click on the link below to give a public comment in support – public comment period is 02/10/2014 – 03/12/14.
Comment

Utah lung cancer survivors: Test your house for radon
Charlie McQuinn didn’t think much about the cracks in the basement floor of his Cottonwood Heights home, where he maintains his office downstairs.”

Preop PET Cuts Lung Cancer Surgery
“Routine preoperative PET imaging led to a significant reduction in unnecessary surgery for non-small cell lung cancer (NSCLC), a review of almost 1,000 cases showed.

Waterford Public Library to hold lung cancer screening discussion
New London – “Radiologist Dr. Louis Mazzarelli will discuss the importance of lung cancer screenings at the Waterford Public Library from 6:30 to 7:30 p.m. March 12.”

Rigorousness of Phase III trials for lung cancer may be declining
“Study Rundown: Advanced NSCLC is an extremely aggressive form of cancer with poor outcomes, and thus has been the subject of many clinical trials over the past several decades. Though many new agents have been developed, overall outcomes remain poor.”

Utah lung cancer survivors: Test your house for radon
SB109 » Effort would seek to inform public about radioactive gas.

“Charlie McQuinn didn’t think much about the cracks in the basement floor of his Cottonwood Heights home, where he maintains his office downstairs.”

LUNG CANCER REVOLUTION? Mizzou researchers patent new testbr> COLUMBIA, Mo 3/6/14 (Beat Byte) -- “A new blood test for lung cancer could detect the disease far earlier than any current method, prolonging and possibly even saving the lives of lung cancer patients, says a Mizzou researcher who patented the test last month.”

Week ending March 2, 2014

Centers for Medicare & Medicaid Services (CMS) takes first steps to cover lung cancer screening – click on the link below to give a public comment in support – public comment period is 02/10/2014 – 03/12/14.
Comment

Bristol-Myers Squibb Announces Charitable Donation of $1 Million to Support Immuno-Oncology Education for Patients and Caregivers
“Bristol-Myers Squibb Company today announced donations totaling $1 million in 2013 to four nonprofit organizations that support patients with cancer. The donations will fund the development and availability of educational materials for patients and caregivers about the emerging field of cancer research and treatment called immuno-oncology. Bonnie Addario Lung Cancer Foundation, Cancer Support Community, LUNGevity, and Society for Immunotherapy of Cancer each received a $250,000 charitable contribution to advance their independent educational initiatives.”

Genentech Asked To Halt Onartuzumab Study In Lung Cancer Due To Lack Of Efficacy
“Genentech, a member of the Roche Group (RHHBY.PK), announced that an independent data monitoring committee has recommended that the Phase III METLung study be stopped due to a lack of clinically meaningful efficacy.”

Lung, Colorectal Cancer Less Likely in Fit Men
“Incorporating a consistent exercise routine can significantly modify risk for CKD patients. Men who maintain good physical fitness have a lower risk of lung and colorectal cancer. Men who maintain good physical fitness have a lower risk of lung and colorectal cancer, according to study findings presented at the 2013 American Society of Clinical Oncology annual meeting.”

A minimally invasive approach to diagnosing lung cancer
SIOUX CITY | “The American Cancer Society published new guidelines in 2013 for lung cancer screening, recommending an annual low-dose CT scan for heavy smokers -- individuals that have smoked the equivalent of a pack a day for 30 years.”

Thoracic surgeon joins Cancer Treatment Centers of America
“Jonathan Kiev, MD, FACS, joined Cancer Treatment Centers of America at Midwestern Regional Medical Center as a thoracic surgeon specializing in advanced and minimally invasive surgical procedures to treat cancers of the lung.”

The Lung Cancer Research Foundation Announces 2014 Grant Cycle Opens
LCRF Grant Application Deadline June 16, 2014.

NEW YORK, Feb. 27, 2014 /PRNewswire-USNewswire/ -- “The Lung Cancer Research Foundation announced that it is accepting submissions of grant requests for medical/scientific research projects covering all aspects of lung cancer research. Submissions from investigators at all levels are encouraged including post-doctoral students to world leaders in the field. The maximum grant amount is $50,000 and the deadline for submission is June 16.”

Advocates push for increased funds to prevent lung cancer
ALBANY (AP) >> “With survival rates for prostate, skin and breast cancer now topping 90 percent, New York health advocates want state funding boosted against far deadlier lung cancer and the carcinogen smoking.”

What’s Happening in Small Cell Lung Cancer Treatment and Survival?
“I recently wrote about a study that showed improving survival rates for people with non-small cell lung cancer - at least those at Moffitt Cancer Center where the study was conducted. As I was feeling hopeful about the study, a reader asked a very important question: What is happening with survival for small cell lung cancer?”

Week ending February 24, 2014

Centers for Medicare & Medicaid Services (CMS) takes first steps to cover lung cancer screening – click on the link below to give a public comment in support – public comment period is 02/10/2014 – 03/12/14.
Public comment

Predictors of bone metastasis, skeletal events in lung cancer identified
“Researchers have identified a range of factors that are associated with the likelihood that a patient with advanced lung cancer will develop bone metastases or skeletal-related events.”

Smoking after Cancer: Does It Even Matter?
“I recently met a new patient, referred to me because of a recent diagnosis of lung cancer. He was just over 70 years old and had been in very good physical condition despite having been a smoker for 50 years. He was intelligent and articulate and admitted he knew the habit was going to “catch up” to him but he decided to continue anyway. We discussed all aspects of his cancer including its causes, stage, treatment options and prognosis. Then he asked a question that many people in his situation ask: “Do I need to stop smoking? What’s the difference anyway?” The answer is a big YES and there are many reasons why.”

Nintedanib plus docetaxel shows second-line efficacy in recurrent NSCLC
“Nintedanib plus docetaxel offers significant efficacy in patients with non-small-cell lung cancer (NSCLC) who experience disease progression after first-line chemotherapy, phase III study results show.”

Commercial molecular tests effective on routine lung cancer samples
NEW YORK (Reuters Health) – “Looking for somatic molecular alterations in non-small-cell lung cancer (NSCLC) is now part of evidence-based practice, and new data show that commercial molecular testing of routinely obtained NSCLC tissue samples is successful in more than 90% of cases.”

'Weeding the garden' technique extends effectiveness of crizotinib for NSCLC
“Patients taking crizotinib for anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) may safely and durably use up to three courses of targeted radiation therapy to eradicate pockets of drug-resistant disease. Eliminating these pockets of resistant disease allows patients to continue treating the overall condition with crizotinib, leading to improved 2-year survival rates compared with patients forced to discontinue the drug sooner, according to a new study.”

Lilly Lung Cancer Treatment Meets Primary Endpoint in Phase III Trial
“Eli Lilly & Co. said Wednesday that its ramucirumab drug reached its primary endpoint in a Phase III study for lung cancer treatment.”

Week ending February 16, 2014

Centers for Medicare & Medicaid Services (CMS) takes first steps to cover lung cancer screening – click on the link below to give a public comment in support – public comment period is 02/10/2014 – 03/12/14.
Public comment

Afatinib ‘first line’ for advanced mutation-positive lung cancer
“Afatinib should be given as a first-line treatment for Asian patients with advanced, epidermal growth factor receptor (EGFR) mutation-positive, non-small-cell lung cancer (NSCLC), researchers recommend.”

Lexington's Beards for Buds aims to raise cancer awareness, money for research
“In 2012, to raise awareness about men's cancers, Jud Davis started a beard-growing contest between the church he attended, Woodford County's Pisgah Presbyterian, and Lexington's Maxwell Street Presbyterian Church.”

Studies show that cooking causes lung cancer
(NaturalNews) “It is common knowledge today that smoking causes lung cancer, however there are many cases of lung cancer diagnosed in people who have never smoked in their lives. So if they've never smoked, what caused their lung cancer we might ask. Studies indicate that it could be as simple as the way they cook their food.”

Lung cancer: Not just a disease of smokers
Some lung cancer patients have never smoked a cigarette

“Cigarette smoking is the main risk factor for most patients who develop lung cancer; however, some patients who are diagnosed with lung cancer have never smoked a cigarette. Physicians today are seeing more non-smokers and light smokers with lung cancer. Why do these people get lung cancer?”

Clinical trial success influenced by biomarker- and receptor-targeted therapies in NSCLC
“Over the past decade, a great clinical focus has been directed at developing new and innovative therapies for advanced non-small cell lung cancer (NSCLC). An analysis of clinical trials evaluating these therapies demonstrates that the cumulative success rate for new agents for advanced NSCLC is lower than the industry-estimated rate. However, biomarker- and receptor-targeted therapies were found to substantially increase clinical trial success.”

Patient Thankful for Lung Cancer Screening Program Preventing Recurrence
Margaret Davis used to start out every day with a Pepsi and a cigarette.

“She says that from the time she was 16, she would smoke a pack to a pack and a half of cigarettes a day.”

Motesanib plus carboplatin, paclitaxel extended survival in NSCLC
“The addition of motesanib to carboplatin and paclitaxel improved OS, PFS and response rates in patients with nonsquamous non–small cell lung cancer, according to results of a phase 3 study.”

High Frequency of EGFR Mutations Found in Asian Population
“Adenocarcinoma histology, female sex, never-smoking status, and Asian ethnicity have been considered the most important factors associated with EGFR mutations in non-small cell lung cancer and response to EGFR inhibitors. A recent study has found that, within the Asian population, the frequency of EGFR mutations associated with other demographic and clinical characteristics is higher than previously reported, even in patients with a history of smoking, suggesting that mutation testing should be done on a broader basis among Asian patients with advanced adenocarcinoma of the lung.”

Fighting cancer, fighing for my terminally ill mom, in a broken health care system
“At the age of 26, it’s hard to come to terms with the reality that my mom is dying. But facing Stage IV lung cancer, doctors say we probably have no more than a few months left together.”

The Real Faces of Lung Cancer: One Woman's Journey to Survive
“In November, during Lung Cancer Awareness Month, I shared the American Lung Association's commitment to extending the lung cancer conversation beyond one month to a yearlong dialogue on lung cancer issues. We are working to address the need for increased research funding - and greater education and awareness about lung cancer and the facts that anyone can get lung cancer and close to 160,000 Americans will die this year because of the disease.”

Week Ending February 9, 2014

Cancer cases likely to increase; lung cancer screenings can help save lives
“Last week, cancer took a spot in the headlines, both with the observation of World Cancer Day (Feb. 4) and the release of a report from the UN which predicts that cancer cases are set to rise by half in the next 15 years. According to the report, “new cases of cancer will rise by half by 2030, reaching 21.6 million per year compared to 14 million in 2012.” Cancer deaths will likely rise from 8.2 million to 13 million per year as the world’s population grows and ages and more people adopt risky lifestyle habits.”

Radiotherapy Survival Benefit Seen in Elderly Patients With Lung Cancer
“Elderly patients with stage III lung cancer who are not candidates for chemoradiotherapy may benefit from radiation therapy (RT) alone.”

Cetuximab plus chemotherapy effective in NSCLC
“The addition of cetuximab to platinum-based first-line chemotherapy significantly improved outcomes in patients with advanced non–small cell lung cancer, according to results of a meta-analysis.”

Lung cancer screening's slow start
“Business has been slow for Allina Health’s lung cancer screening program, despite a new federal recommendation that many chronic smokers over 55 should get checked.”

Getting Cancer Care Support
“As I’ve written many times, we have a family friend who lives across the street and has metastatic lung cancer. Several neighbors, including me, regularly bring food to him and his partner. He’s a retired music teacher and pianist, so I know that one neighbor recently gave him a sheet music collection of Beethoven pieces. Through an open window, I can hear him playing them from time to time. One of his sisters has come to help take care of him for the duration.”

Anti-PD-1 Antibody MK-3475 Advances Into Multiple Tumor Types
“Merck announced the signing of three separate clinical collaboration agreements to evaluate the potential of its investigational anti-PD-1 immunotherapy MK-3475 across multiple tumor types.”

Lung cancer screening strategy a work in progress
SAN DIEGO – “Although the release of the U.S. Preventive Services Task Force grade B recommendations on lung cancer screening in December 2013 marked an important advance in the field, they are not the last words on the issue.”

 

 

February

 

Week Ending February 2, 2014

 

World Cancer Day 2014: New cancer cases to increase five-fold by 2025
February 4 is World Cancer Day

“With a million new cases being reported every year, cancer seems to be tightening its grip on India. Experts say the incidence of the killer disease is expected to rise five-fold by 2025.According to medical professionals, lung and oral cancers were the most common among men while cervix and breast cancer were striking more and more women.”

The role of immunotherapy in NSCLC to expand
SAN DIEGO – “Expect an expanded role of immunotherapy in patients with non–small cell lung cancer, Dr. Roy S. Herbst predicted at the Joint Conference on the Molecular Origins of Lung Cancer sponsored by the American Association for Cancer Research and the International Association for the Study of Lung Cancer.”

Lung Cancer Survival Improving Over Last 20 Years
“Sometimes it seems like we are getting nowhere fast when it comes to lung cancer survival rates1. Despite worthy excitement surrounding genetic testing and targeted therapies, the overall 5-year survival rate2 has remained painfully low - within a percentage point or so from what it was at the time I was born. But that appears to be changing, at least at 3Moffitt Cancer Center where this study was completed. This study, in fact, has me wanting to blow on those New Year's Eve noisemakers that have yet to be packed away.”

New program funds free lung cancer screenings
Iowa – “It's the leading cause of cancer deaths in America; and yet most insurance policies don't cover preventative care for lung cancer exams.

Genesis Philanthropy is still a very new program, and now, through a million dollar donation, they're offering a free way for patients to breathe easier.”

EORTC study shows value of HRQOL assessment in small cell lung cancer
“An EORTC study published in Lancet Oncology found that health-related quality of life (HRQOL) assessment in small-cell lung cancer randomized clinical trials provides relevant added information in studies where the treatment arms do not differ in terms of efficacy. More importantly, it provides valuable information for those treatments where better HRQOL is associated with overall survival benefit. The study also found that even though the overall standard for reporting health-related quality of life was acceptable, there is still need for improvement regarding its reporting in randomized clinical trials to optimize their value.”

Antioxidants increase lung tumor growth in mice
(HealthDay News) – “In mice prone to developing lung cancer, supplementation with antioxidants increases tumor growth, according to a study published in the Jan. 29 issue of Science Translational Medicine.”

After husband's death, Oregon woman warns of radon risk in NW
LAKE OSWEGO, OR (KPTV) – “Is an invisible, odorless killer seeping into your home through the ground? The cancer-causing gas radon kills 22,000 Americans every single year.”

Lung cancer support group forms in High Point
HIGH POINT — “During a span of only four months, Paul Annis found out he had lung cancer, blood clots in both lungs, and diabetes that was signaled by a blood sugar level in the high 800s.”

$99 lung cancer screenings for long-term smokers at HCMC
MINNEAPOLIS (KMSP) – “A government panel recently recommended CT scans for long-term smokers to catch lung cancer in the early stages, and the new screening procedure is being offered for just $99 at Hennepin County Medical Center in Minneapolis.”

Attend a Support Group…from Home
“Each week, I get several notices about patient education programs, support groups, seminars and retreats. They all sound great, and I always have intention to participate. But alas, I make it to about one in ten of these events. Weekdays are tough. I’ve got to herd my kid through homework, piano practice, bath and dinner. Weekends are little better. And aside from busy schedules, most days I’m just too tired to muster the energy for a meeting or seminar. And I’m not even in active treatment!”

Olympia watch: Fight over prior approval for patients heats up
“Insurance companies and doctors are clashing in Washington over a paperwork issue that determines what treatment and medication patients receive — and how quickly they’ll get it.

At issue is prior approval, the requirement that doctors get approval for certain treatments or medications from the insurance company before doling them out. Prior approval is often necessary for anything that is not included in the insurance company’s network or list of drugs.”

 

 

January

 

Week Ending January 26, 2014

 

Family docs: Lung cancer screening advice is a bad prescription
“Last week, the American Academy of Family Physicians (AAFP) broke ranks with a federal task force and other medical organizations by rejecting a new recommendation for annual CT lung cancer screenings for heavy smokers. The AAFP cites insufficient evidence, cost, and risk to patients as concerns.”

American Academy of Family Physicians Denies Utility of Chest CT Screening: A Harmful Slight to the Lung Cancer World
“This week, the American Academy of Family Physicians (AAFP) elected to not follow the lead of the more influential US Preventive Services Task Force (USPSTF), which previously reviewed the information on chest CT screening for high risk patients and recommended it, and said that there is insufficient evidence to support chest CT screening.”

Novel HER2 mutation identified in familial lung adenocarcinomas
“Researchers have identified a novel germline mutation in the transmembrane domain of the human epidermal growth factor receptor 2 (HER2) gene in familial lung adenocarcinomas.”

Silver Cross Leads Coordinated Approach to Lung Cancer Treatment
“Silver Cross Hospital will launch the first multi-disciplinary Lung Cancer Conference in Will County on Feb. 4, 2014. Sponsored by the University of Chicago Medicine, patients will benefit from a team of experienced lung cancer specialists who will coordinate all aspects of care planning so that patients can begin treatment within the shortest time possible.”

Immunotherapy maintenance shows promise in NSCLC
“Results from a phase III trial have shown that tecemotide is no more effective than placebo as maintenance therapy in patients with non-small-cell lung cancer (NSCLC).”

Phoebe Putney will help 200 with lung cancer prevention
ALBANY, GA – “Phoebe Putney Memorial Hospital is starting a new program called “Lung Watch” that will give free services and counseling to 200 people in need.”

Etoposide plus cisplatin remains best for limited-stage SCLC
“Etoposide plus cisplatin, given alongside accelerated hyperfractionated thoracic radiotherapy (AHTRT), remains the gold standard regimen for patients with limited-stage small-cell lung cancer (SCLC), Japanese researchers say.”

U research: Plant may help prevent cancer
Kava reduced lung cancer tissue by up to 99 percent in mice.

“A plant that has been linked to liver damage could one day reduce lung cancer in smokers.

Researchers from the University of Minnesota College of Pharmacy and Masonic Cancer Center authored a study, released earlier this month, linking daily consumption of the kava plant to a 99 percent reduction of lung cancer tissue in mice exposed to tobacco carcinogens.”

Smith: Terminal cancer didn't stand in way of couple's love
“When Don Stranathan opened his heart to Penny Blume, he had a pretty good idea that he would love her forever but they wouldn’t be together long.”

New technologies aid early detection of lung cancer
“More Americans die from lung cancer than any other cancer, and Kentucky leads the nation in both lung cancer incidence and lung cancer death; in fact, Kentucky's death rate of 75 per 100,000 is well above the national average of 55.”

 

Week Ending January 20, 2014

 

Kris Provides Insight Into New Drugs for Lung Cancer
“The FDA awarded new approvals or expanded indications for almost twenty cancer drugs in 2013. To gain further insight, we interviewed Mark G. Kris, MD, the William and Joy Ruane Chair in Thoracic Oncology at Memorial Sloan-Kettering Cancer Center in New York City, on new drugs and emerging trends specifically in lung cancer.”

Molecular and protein-targeting therapies best for lung cancer with KRAS mutation
“Therapies specifically targeting the molecular profile of non-small cell lung cancer (NSCLC) with mutated KRAS, a cancer-causing protein, are the most effective treatment strategies for patients with NSCLC. These findings were presented at the American Association for Cancer Research–International Association for the Study of Lung Cancer Joint Conference on the Molecular Origins of Lung Cancer, January 6-9, 2014, in San Diego, California.”

Radon testing is cheap, easy and necessary
“Radon is invisible, odorless and tasteless, but it is far from harmless. It is the “second leading cause of lung cancer” according to the EPA and Dr. Maria Neira of the World Health Organization.”

Coming a Long Way on Smoking, With a Way to Go
“Fifty years ago this month, Dr. Luther L. Terry issued the first “Surgeon General’s Report on Smoking and Health,” which cited smoking as a cause of lung cancer in men. The hefty report landed like a bombshell on a complacent public, bombarded daily by tobacco advertising and surrounded at work, home and play by people who smoked.”

An Additional $10.5 Million In Federal Research Funding Secured For Lung Cancer
“Today, Lung Cancer Alliance (LCA) proudly announced that an additional $10.5 million for lung cancer research was signed into law by President Barack Obama as part of the FY 2014 Omnibus Appropriations bill. With the approval of this funding, the new total amount of federal research dollars secured to date is nearly $80 million.”

ANN ARBOR: County offers half-price radon test kits
ANN ARBOR — “The Washtenaw County Public Health Department’s Environmental Health Division is observing January 2014 as National Radon Action Month. To promote this event, Washtenaw County is offering half-priced radon home test kits through Jan. 31.”

USPSTF’s Final Recommendation on Lung Cancer and Recommends E-Cigarettes to Help
Washington, DC- “Men’s Health Network strongly supports the U.S. Preventive Services Task Force (USPSTF) recommendation on screening for lung cancer released on December 31, 2013, and it suggests that more emphasis be placed on effective strategies to prevent boys and men from starting to smoke and for realistic strategies to get them to narrow tobacco consumption.”

GSK's lung cancer drug Tafinlar gets FDA breakthrough therapy status
“The US Food and Drug Administration (FDA) has granted breakthrough therapy status for GlaxoSmithKline's Tafinlar (dabrafenib) to treat patients with metastatic BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) who have received at least one prior line of platinum-containing chemotherapy.”

 

Week Ending January 12, 2014

 

Silica exposure may increases lung cancer risk
ATLANTA, Jan. 11 (UPI) -- A meta-analysis found strong and consistent evidence that silica exposure increases lung cancer risk, U.S. researchers say.

U.S. Lung Cancer Rates Continue to Drop: CDC
THURSDAY, Jan. 9, 2014 (HealthDay News) -- As fewer Americans smoke, the number of people who develop lung cancer continues to drop, U.S. health officials report.

TRMC introduces a new lung cancer screening program
Each year in the United States, over 200,000 people will be diagnosed with lung cancer and nearly 160,000 people will die of the disease. More men and women die from lung cancer than any other type of cancer.

Hospital offers free — and new — screenings for lung cancer
he U.S. Preventive Services Task Force has just released a new recommendation for CT (computed tomography) screening for lung cancer.

The guidelines now extend to those people with a smoking history of 30 pack years (calculated by multiplying the average number of cigarettes smoked per day by the number of years a person smoked) who are between the ages of 55 to 80 who quit smoking less than 15 years ago.

Kava May Help Prevent Lung Cancer in Smokers Say University Researchers
AUSTIN, Texas, Jan. 8, 2014 /PRNewswire-USNewswire/ -- Researchers at the University of Minnesota (UM) and Texas Tech University recently studied the effects of a special preparation of the kava root (Piper methysticum) on lung cancer in mice, and have concluded that the chemically defined extract may have the potential to reduce the risk of lung cancer in humans, according to a press release (appended below) issued today by UM.

Peregrine Receives FDA Fast Track Designation for its Lung Cancer Immunotherapy
Peregrine Pharmaceuticals has received Fast Track designation by the U.S. Food and Drug Administration (FDA) for its lead investigational immunotherapy bavituximab for the potential treatment of second-line non-small cell lung cancer (NSCLC). Recently, the company initiated SUNRISE, a pivotal Phase III clinical trial comparing bavituximab plus the chemotherapy docetaxel against placebo plus docetaxel in this indication.

 

Week Ending January 6, 2014

 

Medical milestones of 2013
“The year 2013 was a year where numerous advances were made in the field of medicine especially in areas that have puzzled researchers in the past.”

Working to end cancer, aided by technology, screening
“Few words evoke as much dread or fear as “cancer.” New research and cutting-edge care are redefining what a cancer diagnosis means.”

New marker identified for early diagnosis of lung cancer
“A protein called isocitrate dehydrogenase (IDH1) is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.”

Thoracic surgeon leads new support group for lung cancer patients at Botsford Cancer Center
“"2013 Hour Detroit Top Doc" David Sternberg, MD, a minimally invasive thoracic surgeon and the newest member of Botsford Cancer Center's lung cancer team, will lead a new informal support group for lung cancer patients. The first meeting will be 7-8:30 p.m., Monday, October 21, in the Botsford Cancer Center's Suite 230.”

Marine talks about lung cancer battle
INDIANAPOLIS (WISH) – “A local Marine says he is surviving because of three things in his life — faith, fitness and fight.

I-Team 8 investigated why the Department of Defense and Veterans Affairs were not notifying veterans like Col. Mark Smith that they should be screened for lung cancer after exposure to oil field fire in the Gulf War. Since then, Smith has been fighting cancer and shared with I-Team 8 his new fight.”

Lung cancer: A cloud on China's polluted horizon
BEIJING — “The youngest known lung cancer patient in eastern China is an 8-year-old girl whose home is next to a dust-choked road in heavily industrialized Jiangsu province.”

Targeted investigational therapy potential to overcome crizotinib resistance in lung cancers
“PF-06463922, an investigational drug being developed by Pfizer Inc., has the potential to become a new treatment option for patients who have lung cancer harboring abnormalities in the ALK gene, according to preclinical results presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.”

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Last Updated on Monday, 14 April 2014 16:23
 
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