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Lung Cancer in the News: 2012 PDF Print E-mail

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Week Ending December 31, 2012

Health Talk: Women and lung cancer
“Lung cancer kills more American women than any other type of cancer. In fact, many people are surprised to learn that lung cancer kills more American women than breast cancer and ovarian cancer combined.”

Study shows COPD not an independent risk factor for lung cancer
“Contrary to what some observers believe, a new study concludes that chronic obstructive pulmonary disease (COPD) is not an independent risk factor for lung cancer.”

Cancer Death of Patient Given Smoker's Lung Reveals 40% of Transplanted Lungs Come From Smokers
The family of a UK cystic fibrosis patient who died of cancer after she was given a smoker's lung during a transplant operation is speaking out about her death for the first time.

“Jennifer Wederell's family has started a campaign to encourage more non-smokers to register as organ donors as new statistics revealed that four in 10 lungs used in transplant operations come from donors who have smoked, according to The Telegraph.”

Fighting lung cancer through early detection and prevention
“Out of all the cancers, lung cancer is the leading cause of death among of death among Americans, but the fact is that lung cancer is very preventable, and a new year is a great time to stop smoking. Dr. David Madtes with the Clinical Research Division at Fred Hutch and Director of Seattle Cancer Care Alliance’s Lung Cancer Early Detection and Prevention Clinic talks about this issue. Victoria Evans, a Clinical Social Worker and Chemical Dependency Professional who oversees smoking-cessation services at SCCA, participates in the conversation as well.”

Vaccine for Late-Stage Cancer Fails
Lung cancer vaccine does not improve overall survival for patients with advanced disease

(dailyRx News) “Vaccines are showing promise as medication therapy for patients with advanced-stage lung cancer. A new vaccine, however, recently failed to extend the lives of certain cancer patients.”

Why and How Patients With Lung Cancer Initially Get Diagnosed With the Disease
“UT Southwestern Medical Center researchers are looking into the widespread implementation of computed-tomography (CT) scanning for the early detection of lung cancer in a public heath setting, asking two key questions: Without screening, why and how do patients with lung cancer get diagnosed with the disease in the first place? And what proportion of these cases would be captured by screening efforts?”

Jefferson Establishes New Center for Lung Cancer and Lung Disease
“Thomas Jefferson University and Hospitals announces the creation of the Jefferson – Jane and Leonard Korman Lung Center, made possible through major support from the Jane and Leonard Korman Family Foundation. The partnership will allow Jefferson to better understand lung disease through innovative research and expanded clinical programs for exceptional patient care.”

Lung cancer doesn’t stop Atlanta financial manager
“In the late 1990s, as he was entering his 50s, Atlanta financial manager Jeff Wigbels was a hard-driving marathon runner and triathlete with the health and physique of a man at least a decade younger.”

Week Ending December 16, 2012

The current state of lung cancer treatment
“A review in the December issue of the journal Archives of Pathology & Laboratory Medicine by Paul Bunn Jr, MD, University of Colorado Cancer Center investigator and past president of ASCO, IASLC and AACI describes the current state of lung cancer care.”

COPD Is Not Independent Risk Factor for Lung Cancer, Study Concludes
“Chronic obstructive pulmonary disease (COPD) and lung cancer are two of the most important smoking-related diseases worldwide, with a huge combined mortality bur¬den. Many consider the presence of COPD itself to be an independent risk factor for lung cancer. Others argue that smoking contributes to both COPD and lung cancer.”

Gene variations predicted lung cancer susceptibility in Asian women
“Three gene variations predispose Asian women who have never smoked to lung cancer, according to results of a genome-wide association study.”

Many Lung Cancer Patients Prescribed Inappropriate Drugs
“Just as society wizened to the tinctures of snake oil in centuries past, modern day pharmaceuticals are receiving a good dose of scrutiny - often with similar concern.”

Family fights lung cancer in name of marathoner
“Four months after completing his first marathon in 2011, Scott Garet, 26, underwent an MRI test for pain in his back.”

Lung Cancer Screening Program
PA – “At Holy Redeemer we offer the personalized support that helps smokers, former smokers and those with other lung problems, take a proactive step towards improved health.”

Lung Cancer Remains #1 Killer In New York
“The American Cancer Society Cancer Action Network estimates 8,800 people died from lung cancer in New York state this year.”

Week Ending December 9, 2012

Lung Cancer and African Americans: Know the facts
“First, the bad news. Lung cancer kills more African Americans than any other type of cancer. And African Americans have higher rates of lung cancer than white Americans: for example, from 2003 to 2007, African American men had a 23 percent higher rate of new lung cancer diagnoses than white men. African Americans also have a lower five-year relative survival rate than whites. Furthermore, some studies have shown that African Americans with early-stage disease are less likely than whites to receive surgery, which offers the best chance for a cure.”

Denosumab extended survival in lung cancer with bone metastases
“The monoclonal antibody denosumab, which reduces the incidence of skeletal-related events in persons with bone metastases from solid tumors, was recently shown to improve overall survival in persons with metastatic lung cancer more effectively than did zoledronic acid.”

National audit reveals improvements in lung cancer care
“Lung cancer care in the UK is continuing to make incremental improvements, according to a major NHS audit.”

Cancer fight inspires message to youth
TIMMINS - Norm Julien is a private man.

“Not private in the sense that he doesn't like people. It's quite the opposite actually. Julien estimates he has taught more than 5,000 Timmins residents how to drive over the past 25-plus years as a driving instructor. And he'll never turn down a good conversation about pretty much anything, from politics to sports to people.”

North Star Lodge Offers New Treatment to Patients
YAKIMA, Wash. –“North Star Lodge now offers a new form of radiation treatment for cancer patients. It's the first in the state to have the TrueBeam Linear Accelerator. The equipment is to treat lung, breast, prostate and other types of cancer that might have needed surgery in the past. The machine targets tumors more precisely. Doctors say there are also fewer side effects and patients don't need to be treated as long. Five weeks of therapy can drop down to five days.”

Beaumont Adds Lung Cancer Center
ROYAL OAK — “In 2012, more than 226,000 new cases of lung cancer will be diagnosed in the United States. The good news is that with accurate diagnosis and appropriate treatment, many people diagnosed with lung cancer live long, healthy lives.”

Week Ending December 2, 2012

Cancer research bill adopted as defense bill amendment
“A bipartisan cancer research measure was adopted as an amendment to the Senate defense bill, paving the way for its passage after nearly six years of work.”

Lung Cancer Surgery Longer and Costlier for Obese Patients: Study
“A new research reveals that lung surgeries fall more expensive for obese patients. For the study, researchers analyzed data from more than 19,000 American patients who had a portion of lung surgically removed due to lung cancer between 2006 and 2010.”

Report: Lung Cancer Number One Cancer Killer In New York State
“Lung cancer remains the deadliest form of cancer in New York State. The American Cancer Society Cancer Action Network’s recently-released statistics found there will be an estimated 8,800 lung cancer deaths statewide this year.”

Influence of Advanced Cancer Patient’s Spirituality on Caregiver Depression
“It's not uncommon for family caregivers of people with cancer to experience depression. Sadly, the well-being of caregivers has long been pushed to the back burner, as attention is focused on the immediate needs of the cancer patient.”

Tumor tracking technique may improve outcomes for patients with lung cancer
“A new tumor-tracking technique delivers higher levels of radiation to moving tumors while sparing healthy tissue in lung cancer patients. This technique is moving closer to the clinic.”

Radon Gas 'Targets Everyone'
“The second leading cause of lung cancer isn’t second-hand smoke or genetics. It’s an invisible, odourless, naturally occurring gas called radon.”

House Call: Know the facts about lung cancer
“Patients often ask me, “Other than smoking, what are the most common risk factors for lung cancer?””


Week Ending November 25, 2012

Smokers, Nonsmokers Alike Urged to Learn About Lung Cancer
Knowing symptoms, early detection could cut rates of this deadly disease, expert suggests

(HealthDay News) -- Statistics show that lung cancer kills about 160,000 people a year in the United States and is the country's leading cause of cancer death, but there are steps people can take to reduce their risk, an expert advises.

Lung Cancer Awareness Month: Personalized therapies offer hope
New “designer” or personalized therapies are offering greater hope for lung cancer patients who are told they have an incurable disease.

Region's First High-Risk Lung Cancer Screening Program Now Open
CINCINNATI-Lung cancer screening is now available for Tristate residents who are at an increased risk for lung cancer. Individuals who have smoked a pack of cigarettes a day for more than 20 years and those with a prior lung cancer diagnosis are considered at the highest risk.

Tune in for a Lung Cancer Tweet Chat
No. The birds won't be discussing lung cancer, but there will be plenty of tweeting going on.

On Tuesday, November 27, 2012, The University of California Davis Comprehensive Care Center is sponsoring a tweet chat on Twitter, in honor of Lung Cancer Awareness Month.

SCH offers $99 CT scan that detects lung cancer early
SALEM, OH- A $99 low-dose CT lung cancer screening program started two months ago at Salem Community Hospital can detect cancer the size of a pea in a 3-D high-resolution image of the lungs.

Health Plus: Why lung cancer survival odds could improve
WATERLOO (KWWL) - Lung cancer kills more men and women than any other type of the disease.

Denosumab Wins Survival Test in Lung Cancer
Patients with advanced lung cancer had modest improvement in survival when they received bone-targeted therapy with denosumab (Xgeva) instead of zoledronic acid (Zometa), results of a large randomized trial showed.

Lung cancer lags in research funding
Lung cancer programs receive a fraction of the grants devoted to types that take fewer lives, data show. The stigma of smoking looms large.

“Lung cancer takes more lives than any other cancer. This year it will kill an estimated 160,340 Americans – more than breast, colon and prostate cancers combined.”

Lung cancer kills too many in Kentucky
“November is lung-cancer awareness month and Kentucky has the dubious honor of having some of the highest smoking and lung cancer rates in the country.”

Study Finds Genome Links to Lung Cancer in 'Never-Smokers'
“Recent genomic studies of the world’s worst killer – lung cancer – have run up against a vexing question: Is the disease that affects tobacco users separate from the version that kills people who never smoked?”

Five Things to Know About Lung Cancer
Dana-Farber experts offer life saving information and ways to reduce risk

“More than an estimated 160,000 people in the United States will die from lung cancer this year, making it the country’s leading cause of cancer death.”

Lung Cancer Research Could Get Boost From New Stem Cell Findings
“New research conducted at the University of Cincinnati (UC) Cancer Institute suggests that lung cancer stem cells can be successfully isolated and grown in a preclinical model. Such a process could provide a new method for investigating immunotherapy treatment options that target lung cancer stem cells.”

Stanford lung cancer experts address new screening guidelines
“Nearly 50 years after the first Surgeon General warnings linking smoking to cancer appeared on cigarettes packages, millions of Americans have managed to break the addictive habit. And while a decrease in the numbers of smokers provides great reason to celebrate, lung cancer remains the leading cause of cancer death. The damage that smoking does to the lungs still means a far higher risk of developing cancer.”

Week Ending November 18, 2012

Lung cancer lags in research funding
Lung cancer programs receive a fraction of the grants devoted to types that take fewer lives, data show. The stigma of smoking looms large.

“Lung cancer takes more lives than any other cancer. This year it will kill an estimated 160,340 Americans – more than breast, colon and prostate cancers combined.”

Lung cancer kills too many in Kentucky
“November is lung-cancer awareness month and Kentucky has the dubious honor of having some of the highest smoking and lung cancer rates in the country.”

Study Finds Genome Links to Lung Cancer in 'Never-Smokers'
“Recent genomic studies of the world’s worst killer – lung cancer – have run up against a vexing question: Is the disease that affects tobacco users separate from the version that kills people who never smoked?”

Five Things to Know About Lung Cancer
Dana-Farber experts offer life saving information and ways to reduce risk

“More than an estimated 160,000 people in the United States will die from lung cancer this year, making it the country’s leading cause of cancer death.”

Lung Cancer Research Could Get Boost From New Stem Cell Findings
“New research conducted at the University of Cincinnati (UC) Cancer Institute suggests that lung cancer stem cells can be successfully isolated and grown in a preclinical model. Such a process could provide a new method for investigating immunotherapy treatment options that target lung cancer stem cells.”

Stanford lung cancer experts address new screening guidelines
“Nearly 50 years after the first Surgeon General warnings linking smoking to cancer appeared on cigarettes packages, millions of Americans have managed to break the addictive habit. And while a decrease in the numbers of smokers provides great reason to celebrate, lung cancer remains the leading cause of cancer death. The damage that smoking does to the lungs still means a far higher risk of developing cancer.”

Week Ending November 12, 2012

Screening for Lung Cancer Saves Lives
SEATTLE – “Lung cancer is the No. 1 cause of cancer deaths in the United States, despite the fact it is largely preventable. For people at high risk of developing lung cancer, such as current or former longtime smokers, screening for the disease with low-dose CT scans is now a viable option that has been shown to significantly reduce mortality rates. In conjunction with National Lung Cancer Awareness Month, Seattle Cancer Care Alliance (SCCA) wants to raise awareness about the importance of prevention and early detection for at-risk populations.”

Painkiller and Lung Cancer Research Pays Off for California and Oregon Students With Siemens Competition Regional Win at California Institute of Technology
“Months of dedication and hard work in science, technology, engineering and math (STEM) paid off tonight for three students named National Finalists in the Siemens Competition in Math, Science & Technology, the nation's premier research competition for high school students. Research on a promising "painless painkiller" earned top honors and the $3,000 Individual scholarship for Raghav Tripathi of Portland, Oregon. Research that could help improve the treatment and prevention of lung cancer won the $6,000 Team scholarship for Thomas Luh of San Jose, California, and Joy Jin of Palo Alto, California.”

My Passion: Screening guidelines needed for lung cancer
“John is lucky to be alive today. Last January, he went to the doctor with what we thought was persistent laryngitis. Our family doctor did an exam, listened to his chest and had an X-ray taken. He showed us the picture: A mass growing in the lung, pressing against the laryngeal nerve was causing the loss of voice.”

Radon: Could a silent killer be lurking?
“Kaye Ranger-Lefler was in perfect health until last fall, when episodes of lower back pain began regularly striking her a few hours after mealtime.”

New Resource Provides Lung Cancer Support from Day One
“The American Lung Association has launched Facing Lung Cancer: Support from Day One, a new web-based resource designed to guide and support those living with lung cancer and their loved ones during every stage of their disease. Lung cancer is a complex and life-changing disease—but those who are living with lung cancer are not alone.”

George Edwards Jewelers promoting lung cancer awareness
“November is Lung Cancer Awareness Month and George Edwards Jewelers, located at 2131 Sawyer Dr., Wheatfield, NY is “GOING WHITE” for the month of November.”

Cancer patients treated to homemade scarves for Lung Cancer Awareness month
PEORIA – “Sheila Kimmey knit, knotted and pulled 130 scarves over the course of two months, averaging more than two of the accessories a day.”

Supportive spouse may improve lung cancer survival
“Married patients with locally advanced non–small cell lung cancer were likely to survive longer after treatment than patients who were single, according to study results presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology.”

Week Ending November 4, 2012

Toxicity Shuts Down Avastin Trial in NSCLC
“Unacceptable toxicity has at least temporarily derailed efforts to incorporate the angiogenesis inhibitor bevacizumab (Avastin) into chemoradiation for inoperable non-small cell lung cancer (NSCLC), investigators have concluded.”

Stereotactic Radiation May Help in Early Lung Cancer
“Compared with historical reports, the use of stereotactic body radiation therapy in inoperable early lung cancer appears to result in longer 3-year and 5-year survival, Japanese researchers reported here.”

High riboflavin linked to low lung cancer risk
“Maintaining an adequate intake of riboflavin may help reduce risk of lung cancer, according to a new study in Cancer Causes and Control.”

Small-Fraction RT May Aid Inoperable NSCLC
“Accelerated hypofractionated radiation therapy led to a 3-year locoregional control rate of about 80% in patients with inoperable early-stage non-small cell lung cancer (NSCLC), a small retrospective study showed.”

Tewksbury lung-cancer survivor wants to pay it forward
TEWKSBURY – “Susan Appleby went through chemotherapy, radiation and surgery before undergoing the targeted therapy she said saved her life.”

A breakthrough in cancer research at WFU is a sign of progress and hope
“The most tenacious and deadly types of cancer may soon have an equally tenacious adversary, thanks to the research of a medicinal chemist at Wake Forest University. We’re proud to see this and other promising life-saving research going on in Winston-Salem.”

Coventry lung cancer support group celebrates 13th anniversary
UK – “The Coventry Lung Cancer Support Group meets every month at University Hospital in Walsgrave.”

Lahey Clinic to offer lung cancer risk assessment for veterans Nov. 8
“Lahey Clinic is calling on all Veterans in the area to call or come in for a risk assessment for lung cancer.”


Week Ending October 28, 2012

The Cutting Edge
New surgical treatment options offer hope to thousands

“When Dr. Amir Abolhoda recently performed robot-assisted lung cancer surgery at UC Irvine Medical Center — the first procedure of its kind in Orange County — it marked the latest leap in the fast-evolving field of robotics.”

Dacomitinib Bests Erlotinib in Advanced Non–Small Cell Lung Cancer
“Investigators are reporting improved progression-free survival (PFS) after treatment with the investigational agent dacomitinib compared with erlotinib in patients with non–small cell lung cancer (NSCLC) experiencing progression during chemotherapy.”

WellStar offers free lung cancer screening to vets
ATLANTA (CBS ATLANTA) – “WellStar Health System is reaching out to local military veterans to receive lung cancer and respiratory risk screenings during a one-day special event to honor veterans.”

Chandler Regional Medical Center First in Arizona to Perform Lung Procedure for Cancer Patients
CHANDLER, Ariz.– “The first lung brachytherapy (internal radiation therapy) procedure in Arizona, utilizing Cesium-131 (a shorter half-life isotope that minimizes radiation exposure to surrounding tissues) will take place at Chandler Regional Medical Center, a Dignity Health™ Member on Oct. 24, 2012.”

Week Ending October 14, 2012

Abraxane: Breast Cancer Drug Approved By FDA To Treat Lung Cancer
“U.S. health regulators on Friday widened the approved use of Celgene Corp's breast cancer drug Abraxane to include treatment for non-small cell lung cancer, the most common form of lung cancer.”

Benefits of Home Exercise for People With Stage 4 Lung Cancer and Colon Cancer
“Nobody needs to look far to hear about the benefits of exercise. But what about situations in which exercise is the last thing on anyone's mind. For example, if you are coping with stage 4 lung cancer or stage 4 colon cancer?”

New breath test could diagnose chronic disease and cancer
(CBS News) “Dogs have long been known for their powerful noses and scientists are now trying to develop "electronic noses" to mimic this canine sense, in an effort to detect diseases. Dogs have been credited with sniffing out cancer with this super-sense and new medical breath tests are promising similar diagnostic capabilities.”

Facebook page makes a difference for Lowman man dealing with mom's lung cancer
“Sometimes, making a difference in someone’s life is as simple as being a friend. About a year ago, Ray Naylor of Lowman was watching football on a Sunday afternoon when he noticed the players were donned in pink. At halftime, commentators mentioned it was for breast cancer awareness.”

Fire, but no smoke: Non-smoking Crown Point woman survives lung cancer
“No one could have been more surprised than Patricia Ross when she was diagnosed with lung cancer. “Lung cancer!” Ross says. “I never touched a cigarette in my life. I was shocked. Everyone was.””

With lung cancer, quitters do better than smokers
(Reuters Health) –“Younger people with advanced lung cancer who quit smoking more than a year before their diagnosis survive longer than those who continue smoking, according to a new study.”


Week Ending September 30, 2012

Pfizer Lung Cancer Drug Doubles Benefit, Researchers Say
“Pfizer Inc. lung-cancer medicine Xalkori extended the lives of patients without their disease worsening for twice as long as the standard therapies, according to a study sponsored by the New York-based drugmaker.”

Ariad lung cancer drug shrinks tumors in small trial
(Reuters) – “A small early-stage trial of Ariad Pharmaceuticals Inc's experimental pill AP26113 showed it shrank tumors in eight out of 11 lung cancer patients with a genetic mutation in a gene known as ALK.”

Lilly Releases Phase II Results for Monoclonal Antibody Ramucirumab in Lung Cancer
“Eli Lilly and Company (NYSE: LLY) today announced new data from two Phase II ramucirumab (IMC-1121B) trials in patients with non-small cell lung cancer (NSCLC). Results were presented today during the Lung Cancer – Metastatic Poster Session at the ESMO 2012 Congress (European Society for Medical Oncology), 1:00 p.m. – 2:00 p.m. CET, in Vienna, Austria.”

OncoGenex starts phase-3 trial of lung cancer drug
BOTHELL, Wash. — “Drug maker OncoGenex Pharmaceuticals has started its third late-stage clinical trial of a drug for treating a type of lung cancer.”

Health Matters: Screening for lung cancer saves lives
“There is big news rocking the world of cancer care. For the first time there is strong evidence that lung cancer screening does save lives. Take a moment to reflect -- among you, who has not had a close friend or family member with lung cancer? Did you know that lung cancer is the leading cause of death from cancer in both men and women?”

Uncovering the secrets behind lung cancer
“If you think lung cancer only affects smokers, you’re not alone. Many people believe this, but the truth is, anyone can get lung cancer. You can be young or old, male or female, a smoker or a non-smoker.”

Life Technologies launches new molecular test to detect lung cancer
Life Technologies Corporation, a biotechnology company, has launched Pervenio Lung RS.

“According to the company, the molecular test has been documented to identify early stage lung cancer patients who are at high risk for mortality following surgery. It also fulfills the need for prognostic information to guide preventative treatment and improve disease management.”

Week Ending September 23, 2012

Volleyball coach fights cancer with attitude
“Don't admire Angie McKinnell because she is a four-time cancer survivor at age 32. Although many understandably do.”

Woman runs to defeat lung cancer
“Kelcey Harrison is running across the United States to eliminate lung cancer. She is doing it to help fulfill her childhood friend's dream to "beat (lung cancer) for all people."”

HER2 May Impact Lung Cancer Therapy
Overcoming therapeutic resistance that inevitably develops is one of the major challenges in treating lung cancer.

“Non-small cell lung cancers that harbor mutations in the epidermal growth factor receptor (EGFR) are initially responsive to targeted therapies known as EGFR tyrosine kinase inhibitors (TKIs). However, most patients eventually develop resistance to these therapies.”

Too many' cancers only diagnosed in A&E, study suggests
Almost a third of cancers in the over-70s are only diagnosed when a patient is admitted to hospital as an emergency, a study suggests.
“The National Cancer Intelligence Network looked at nearly 750,000 patients' experiences between 2006-08 in England.”

Boehringer submits new lung cancer drug
Boehringer Ingelheim has filed its new lung cancer drug with the EMA.

“Afatinib is the latest targeted therapy for lung cancer, which will add to the treatment choices in the hard-to-treat therapy area.”

Radiation Pneumonitis in Stage 3 Lung Cancer
“Unfortunately, the slang phrase "slash, poison, burn," bares a hint of reality in describing the side effects of cancer treatment. Treatment isn't without side effects -- and they are sometimes as dreaded as cancer itself. Just as chemotherapy is well-known for the "poison" side effects of hair loss and nausea, radiation therapy is known for its "burns." And for people with lung cancer, the tissue that is "burned" is often the lungs.”

Smokers With Lung Cancer Have Tenfold Genetic Damage
“The tumors of smokers who develop lung cancer have ten times more genetic damage than those of never-smokers who develop the disease, according to a study published online in the journal Cell this week.”

Week Ending September 16, 2012

Studies offer ‘panoramic view’ of lung cancer
Three genome-sequencing trials may help to revamp treatments for the world’s most deadly cancer.

“Lung cancer causes more deaths than any other form of cancer. About 1.6 million people worldwide are diagnosed with the disease each year, with fewer than 20% still alive five years later.”

End-Running Cancer Resistance to Targeted Therapies
“Targeted therapies directed against receptor-activated protein kinases have transformed clinical management of many cancers, but keeping a step ahead of inevitable cancer resistance to these drugs resembles the game of whack-a-mole.”

Couple Share Deadly Lung Cancer and Undying Love
“Don Stranathan and Penny Blume are middle-aged lovers spending a glorious month traveling on the West Coast, savoring each moment as if it were their last. And it may be; both have terminal lung cancer.”

Lung Cancer Study Sheds Light on Treatment Options
Researchers at the Washington University School of Medicine collaborated on the project, University City Patch reported.

“A cutting-edge analysis of a common type of lung cancer will help scientists improve prevention, detection and treatment, the Washington University School of Medicine reported via University City Patch.”

'AdamPalooza' Raises Cancer Research Funds
School board member's backyard event aids Memorial-Sloan Kettering center.

“Huntington school board trustee Adam Spector recently ran an informal cancer-research fundraiser in his backyard.”

Study shows breath analysis could help diagnose pulmonary nodules
DENVER – “A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign and malignant pulmonary nodules. The study looked at 74 patients who were under investigation for pulmonary nodules and attended a referral clinic in Colorado between March 2009 and May 2010.”

Week Ending September 09, 2012

Cancer Study Points to Tighter Pairing of Drugs and Patients
“The first large and comprehensive study of the genetics of a common lung cancer has found that more than half the tumors from that cancer have mutations that might be treated by new drugs that are already in the pipeline or that could be easily developed.”

NNY lung cancer rates linked to smoking
“The American Cancer Society released a report in July 2012 entitled “The Cancer Burden in New York State.” This report states that more than 107,000 New Yorkers received a cancer diagnosis in 2011 and more than 34,000 died from the disease. A different way to look at that figure is that roughly 2,000 New Yorkers are diagnosed with cancer and 660 individuals die from cancer each week.”

Radioactive particles in cigarette smoke cause lung cancer
“At least 70 chemicals in cigarette smoke can cause lung cancer including benzene, formaldehyde, acetone, tar, nicotine, arsenic and hydrogen cyanide. But a new study most recently published in Nicotine & Tobacco Research reveals that a major cause of the deadly disease is a type of radioactive particles.”

Discovery Could Help in Treatment of Deadly Lung Cancer
Scientists have discovered two molecules in the cell that may open new doors in the treatment of a highly aggressive form of lung cancer called small cell lung cancer.

“Scientists have discovered two molecules in the cell that may open new doors in the treatment of a highly aggressive form of lung cancer called small cell lung cancer (SCLC). Small cell lung cancer accounts for about 15 percent of all lung cancers. This type of cancer spreads faster than non-small cell lung cancer. SCLC is the most aggressive form of cancer and is found mainly in people who smoke. The cancer cells in this type of cancer are small, but grow fast and spread to other parts of the body like brain, liver and bones.”

Living with someone 'aids lung cancer recovery
“Being married, or living with someone, improves lung cancer patients' chance of survival, US experts say.

The University of Maryland team studied 168 patients with advanced non-small cell lung cancer, the most common kind, treated between 2000 and 2010.”

WorkSafeBC to provide CT scans for workers sickened by asbestos
“Workers suffering from illnesses caused by on-the-job asbestos exposure will soon be eligible to receive diagnostic CT scans funded by WorkSafeBC in an effort to diagnose lung cancer sooner and reduce mortality from the disease.”

Lilly lung cancer drug fails to meet main goal in Phase 3 study
(Reuters) – “Drugmaker Eli Lilly and Co said on Thursday its late-stage lung cancer study failed to meet its primary goal of improved overall survival for patients with nonsquamous non-small cell lung cancer.”

Upstate Cancer Center offers first lung cancer screening program in CNY
Syracuse (WSYR-TV) – “Central New York’s first lung cancer screening program is now available at Upstate Cancer Center. For the first time ever, you'll be able to sign up for a CT scan to check for lung cancer, while it's still small and curable.”

Novel therapeutic targets identified for small cell lung cancer
PHILADELPHIA — “Newly discovered molecular differences between small cell lung cancer and nonsmall cell lung cancer have revealed PARP1 and EZH2 as potential therapeutic targets for patients with small cell lung cancer, according to the results of a study published in Cancer Discovery, a journal of the American Association for Cancer Research.”

Lung cancer cases on the rise in non-smokers, study suggests “Lung cancer rates are increasing among women and people who have never smoked, a new study finds.”

Cancer Center investigator remembered as lung cancer researcher, scholar and gentleman
“Longtime University of Colorado Cancer Center Investigator Alvin M. “Al” Malkinson died Aug. 3, 2012 at his Boulder, Colo. residence.”

Week Ending September 2, 2012

Broaden public's access to lung cancer screening
Each year, families in New Jersey and throughout the United States receive the devastating news that a loved one has been diagnosed with lung cancer. This news is particularly hard to bear, as lung cancer is one of the most difficult cancers to treat in later stages after symptoms appear. The overall survival rate of patients who receive a late diagnosis is just 15 percent. In light of this startling statistic, The American Association for Thoracic Surgery issued new guidelines in July strongly recommending that high-risk patients with long histories of heavy smoking undergo annual low-dose CT scans.

VA to try 'phased' approach to lung cancer CT screening
The U.S. Department of Veterans Affairs said it would embark on a "phased implementation" of CT lung cancer screening for veterans after taking inspiration from a national trial that found the scans could help save lives among certain high-risk populations, DOTmed News has learned.

Clinical trial of lung cancer vaccine in Scotland
Researchers at Aberdeen Royal Infirmary are recruiting participants as they prepare to head up a global clinical trial of the therapeutic lung cancer vaccine known as BV-NSCLC-001. The vaccine, which treats the most common form of the disease – non-small cell lung cancer – was developed by Aberdeen-based biopharmaceutical firm, Bioven.

Not all lung cancer patients who could benefit from crizotinib are identified by FDA-approved test
Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails – such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA approved the drug crizotinib to treat these ALK+ lung cancer patients, who were likely never smokers. Informed doctors use the test called a FISH assay to check for the EML4-ALK fusion gene, and then if the test is positive, ALK+ patients benefit greatly from crizotinib. A recent University of Colorado Cancer Center case study published in the Journal of Thoracic Oncology describes the never-before-seen case of a patient who tested negative for EML4-ALK fusion based on the well-defined criteria for FISH assay as approved by FDA, but nevertheless experienced remission after treatment with crizotinib.

Vitamin D Fights Breast Cancer, Colon Cancer, Lung Cancer and Lymphoma – Study
Tuesday Aug 28, 2012 (foodconsumer.org) -- A new study in Cancer Causes and Control suggests that maintaining a high level of serum vitamin D may help fight a variety of malignancies including breast cancer, colon cancer, lung cancer and lymphoma. Previous studies suggest taking vitamin D supplements may fight prostate cancer as well.

ArQule plunges on delay in cancer drug study
ArQule's Japanese partner Kyowa Hakko Kirin Co. temporarily suspended enrollment of patients in a late-stage trial of tivantinib as a treatment for lung cancer. Kyowa made the decision on a recommendation from a safety monitoring committee because some patients are believed to have contracted interstitial lung disease.

New Virginia G. Piper Cancer Center-TGen study targets small-cell lung cancer
SCOTTSDALE, Ariz., Aug. 29, 2012 /PRNewswire-USNewswire/ — A Phase I/II, multi-center trial designed to test the safety and preliminary efficacy of a first-in-class cancer treatment opened worldwide today at the Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen). PR610 is designed to become activated in tissues with low levels of oxygen, which is characteristic of many cancers. This “targeted” approach should deliver more active drug to cancer tissue and less active drug to normal tissue.

Lung Cancer Risk Unaffected by Metformin Use in Diabetes
Patients with type 2 diabetes who take metformin do not have a reduced risk of lung cancer, in contrast to previous observational studies, according to a study published online Aug. 24 in Diabetes Care.

Domestic coal use linked to substantial lifetime risk of lung cancer in Xuanwei, China
The use of "smoky coal" for household cooking and heating is associated with a substantial increase in the lifetime risk of developing lung cancer, finds a study from China published on bmj.com today. This represents one of the strongest effects of environmental pollution reported for cancer risk in any population, say the authors. It also underlines the importance of taking action to minimize exposure to the most hazardous types of fuel.

Soul man Curtis Salgado back on the road after fighting cancer
As he has done for more than three decades, Curtis Salgado is out on the road, bringing his powerhouse soul music to clubs like the Zoo Bar. On this trip, however, Salgado is “playing catch up.” Earlier this year, he had to cancel tour dates when he was hit with a recurrence of the lung cancer he thought he had beat five years ago. “I just had a surgery that removed the lower lobe of my left lung,” Salgado said. “I feel good. The doctors were surprised and I was surprised. I was out of the hospital in three days. I recovered in four weeks and I don’t feel any different. I’ve now got like a lung and a half, but I don’t feel any different. Maybe walking up a hill, but not singing and playing harmonica.”

New treatment for lung cancer
Lung cancer is the deadliest form of cancer and some local doctors have a new weapon in their arsenal.

"That's the only attitude to have, that you're going to be fine," said Charlie Price. Not even a potentially deadly diagnosis like lung cancer can get Charlie Price down. "It takes a lot to scare me," said Price. Price got the news last November. Doctors acted quickly and aggressively and removed a portion of his right lung. But further tests revealed more cancer. So Price's doctor suggested he try a new treatment. "Once we are close the lesion, we take the guide out and take the biopsy and also put in the markers," said pulmonologist Dr. Sunil Lalla.


Week Ending August 26, 2012

Equal Access to Treatment May Improve Lung Cancer Survival in African Americans
A new study I reviewed today had me yodeling off of my deck with joy. A comparison of black patients and white lung cancer patients in the U.S. Military Health System (MHS), found that there was no significant difference between the two groups in survival rates.

Girl runs across country to raise cancer awareness
You might have driven past her earlier this week without even noticing. Wearing black running capris and her long blonde hair pulled back into a tight ponytail, Kelcey Harrison looked like any other runner jogging throughout Beaver County. But she isn’t just another local resident out logging a few miles along River Road or grabbing a few laps at the high school track. Western Pennsylvania was just one of the many stops along her route as she runs from New York City to San Francisco to raise awareness for the leading cancer killer for both men and women in the United States -- lung cancer.

Drivers exposed to diesel exhaust face increased lung cancer risk
Researchers are calling for engineering and administrative controls to reduce the incidence of lung cancer among professional drivers. The authors of a new study also say the government and researchers should step in and help.

Varian backs radiosurgery vs. traditional surgery study
Varian Medical Systems said last week it's contributing funds to help with patient accrual efforts for a National Cancer Institute-sponsored, multi-center study comparing radiosurgery against the knife-based kind for high-risk patients with early-stage lung cancer. A Varian spokeswoman told DOTmed News the Sunnyvale, Calif-based company will kick in some funds and provide other help to support the study's goal of accruing 420 patients over a five-year period. As of June, 45 centers had qualified to participate in the phase III trial, the company said.

Early stage lung cancer blood test to simplify and standardize detection gets $1M grant
Detecting non-small cell lung cancer in its early stages could soon be as easy as getting a blood test in a routine checkup. A group of researchers is taking advantage of the advances in biomarker technology with a test that could improve outcomes for patients with one of the leading causes of cancer-related deaths.

Computer model assesses risk for lung cancer
A computer risk-prediction model assessing a patient's risk for developing lung cancer proved more accurate than assessments based on smoking duration or family history, a new research study finds.

Using Virtual Health Care Environments to Achieve Real-World Results
UCSF School of Nursing Researchers Test Technology to Improve Health

On the surface, Parkinson’s disease and lung cancer have little in common, except that both have a devastating effect on many people’s lives. But two researchers from the UCSF School of Nursing Department of Physiological Nursing have discovered another link: the potential to use virtual electronic environments to help some patients manage these illnesses better than they can with existing methods.

Pfizer's Phase III non-small cell lung cancer study meets primary endpoint
Pfizer Inc. has announced that the PROFILE 1007 study met its primary endpoint, demonstrating that XALKORI significantly improved progression-free survival, or PFS, when compared with pemetrexed or docetaxel, in previously treated patients with anaplastic lymphoma kinase, or ALK-positive advanced non-small cell lung cancer, or NSCLC.

Week Ending August 19, 2012

Health groups renew push to ban smoking at casinos
KANSAS CITY, Mo. (AP) — “Kansas City health advocates have started a new push to get smoking banned at area casinos, but it's not going to be an easy fight in a competitive industry with lots of financial clout.”

Radon gas deadlier than thought: Radioactive substance causes 16% of lung cancer cases, Health Canada says
“Radon seeping invisibly into some Canadian homes causes hundreds more lung-cancer deaths a year than previously thought, a Health Canada study based on a recent testing blitz has concluded.”

‘I had a cough for two years before my lung cancer was discovered'
SCOTLAND – “Pensioner Tom Muir dismissed his persistent cough as nothing more than a symptom of old age.”

Getting the Best Care for Lung Cancer
What lung cancer patients need to know

“In the second of our series on lung cancer, we continue our conversation with one of the nation's experts on the subject. D. Ross Camidge, MD, PhD, is a well-known lung cancer specialist and director of the thoracic oncology clinical program at the University of Colorado.”

Ongoing Trials in Lung Cancer Focus on Combination Therapies
“Research presented at the American Society of Clinical Oncology Annual Meeting in June included these two clinical trials in advanced, metastatic non-small cell lung cancer (NSCLC).”

NYU Langone offers chance to participate in lung cancer early detection study
“NYU Langone Medical Center is a pioneer in lung cancer screening and offers comprehensive screening for individuals at risk for lung cancer. The NYU Langone Lung Cancer Screening Center is distinguished by its multidisciplinary approach and wealth of experience and is under the direction of the Divisions of Pulmonary Medicine, Thoracic Radiology and Thoracic Surgery. NYU Langone offers patients a personalized consultation with a team of experts across a range of specialties.”

Week Ending August 12, 2012

Common Genetic Mutation Confers TKI Resistance in CML
“A common genetic mutation appears to play a role in resistance to tyrosine kinase inhibitors among certain types of cancer, including chronic myeloid leukemia (CML) and EGFR-mutated non–small-cell lung cancer (NSCLC), according to a new study.”

Lung Cancer Alliance Announces Breakthrough on CT Screening for Veterans
“Today, Lung Cancer Alliance (LCA) announced that the Department of Veterans Affairs (VA) has agreed to move forward on CT screening for veterans at high risk for lung cancer. This was communicated to Laurie Fenton Ambrose, LCA President & CEO in written correspondence by VA Under Secretary for Health Dr. Robert A. Petzel.”

New early lung cancer detection program offers free CT scans to Nevada Test Site workers
“Years of exposure to radiation, asbestos and other construction materials at the Nevada Test Site have left many former workers with health ailments related to their jobs, including increased incidences of cancer.”

Lung cancer research fund recently dedicated
“The Cooper Foundation of Cooper University Hospital and Ponzio’s Diner-Bakery-Bar recently dedicated the Jim Fifis Lung Cancer Research Fund at Cooper Wall of Hope in memory of the late Ponzio’s owner.”

Lung cancer patients can be screened for ALK-inhibitor suitability
“Anaplastic lymphoma kinase (ALK) gene status in patients with lung adenocarcinoma can be determined non-invasively using circulating tumor cells (CTCs), research shows.”

New lung clinic identifies risk for cancer
“There is new hope for improving survival from the number one cancer killer in the U.S. MidMichigan Gratiot Cancer Center has launched a new lung clinic, offering patients a comprehensive approach to screening individuals at high risk for lung cancer. Patients are first screened over the telephone and, if criteria are met, follow-up appointments are arranged which include testing, result evaluation and treatment development.”

Week Ending August 5, 2012

Six hospitals join CoC ProvenCare Lung Cancer Collaborative
“Six more hospitals have joined a national pilot study already under way to promote evidence-based evaluation and treatment standards for patients with non-small cell lung cancer (NSCLC). Patients with this type of lung cancer are also candidates for an operation called "lung resection."”

PET/MRI Comparable to PET/CT in Staging Lung Cancer
“PET plus MR imaging offers comparable diagnostic image quality and tumor delineation in staging of lung cancer to PET plus CT — with less radiation exposure to the patient, researchers reported in a study published in the journal Radiology.”

Battling Her Lung Cancer And Everyone Else's
“The stigma surrounding lung cancer bothers Diane Legg. "Most often the first question asked is, 'Did you smoke?'" she said. "No other disease, nobody asks such an in-your-face question. Most people who have a heart attack, they don't ask if they smoked.”

A Breath of Fresh Air
Albert Lea, MN - “Statistics show that every year in the United States, 3,000 people die of lung cancer because of exposure to secondhand smoke. It contains 69 chemicals that are known to cause cancer.”

Cancer experts push lung screening
“Despite research showing that the practice saves the lives of those with the cancer that kills the most Americans every year, screening for lung cancer is far from routine.”

A Northeast Portland couple celebrates love while battling cancer
“A wedding reception. A celebration of life, for someone living. A living wake, because he's dying. On a sunny Saturday afternoon in Portland, friends and family gathered at a red house on North Prescott Street to celebrate Gary Cash and Steve Mann.”

Support For The Lung Cancer Mortality Reduction Act Continues To Grow
“Today, as Congress prepares for its summer District Work Period, Lung Cancer Alliance (LCA) announced that over 100 members of Congress have now signed on as co-sponsors of the Lung Cancer Mortality Reduction Act (S.752/H.R.1394) which is the first of its kind legislation calling for a coordinated and comprehensive federal plan to address all aspects of lung cancer.”


Week Ending July 29, 2012

Emotional Challenges of Family Caregivers of Lung Cancer Patients
“Caring for a loved one with cancer can be immensely rewarding, but challenging and distressing at the same time. Studies suggest that efforts need to be made to assist family caregivers in ways to take care of their own emotional needs, while they provide physical and emotional support for their loved one with cancer.”

Social media strengthens a local man in his fight against cancer
POTTSBORO, TEXAS – “Like hundreds across the nation, a Grayson County man is battling lung cancer.”

Gainesville a major contributor for cancer research and care
GAINESVILLE - “Georgia CORE, the Center for Oncology Research and Education, has developed an online information center that profiles nearly 50 cancer clinical trials being conducted in Gainesville, including a Georgia CORE-sponsored study for patients with advanced non-small cell lung cancer. Timothy M. Carey, MD of Northeast Georgia Medical Center is a lead investigator for the trial.”

Cancer screening for smokers Aug. 2 in Palm Springs
“Mizell Senior Center in Palm Springs will hold a special cancer screening for smokers at 1 p.m. Thursday Aug. 2 with Dr. Eric Presser also presenting a seminar on new guidelines from three medical studies on lung cancer screenings for smokers ages 55 to 74.”

Picture a battle with cancer
Lilly Oncology on Canvas exhibit makes powerful statement to patients

“Marsha Jenney, diagnosed with lung cancer in January 2011, became a frequent visitor to the Richard A. Henson Cancer Institute at Peninsula Regional Medical Center on June 18. That was when she began daily radiation and infusion chemotherapy treatments to battle the disease.”

Lung spots less dangerous than patients think
NEW YORK (Reuters Health) – “Patients learning they have a "spot" on their lung often assume they have cancer, according to a new study - but that's usually not the case.”

New Biomarker For Common Lung Cancer Predicts Responses To Chemotherapy
“Patients with the most common type of lung cancer are notoriously insensitive to chemotherapy drugs, including cisplatin. New findings related to the cellular pathways that regulate responses to cisplatin have now been published by Cell Press on July 26th in the journal Cell Reports. The findings reveal a potential biomarker that can be used to predict how these patients will respond to chemotherapy, as well as the patients’ overall prognosis, paving the way for personalized treatment strategies.”

Report Finds NYC Has Lower Lung Cancer Rates Than Upstate
“New Yorkers who commonly associate New York City with damaging rates of pollution may be surprised to learn that upstate New York has a higher cancer rate than downstate, and in fact, it really has nothing to do with pollution.”

Week Ending July 22, 2012

New Lung Cancer Screening Guidelines for Patients Available from NCCN
“NCCN has released the NCCN Guidelines for Patients(TM): Lung Cancer Screening, available free of charge on NCCN.com and NCCN.org. The NCCN Guidelines for Patients(TM) is a tool to help patients and their caregivers take a more active role in prevention and treatment decisions.”

Marshall scientist awarded NIH grant for lung cancer research
“A Marshall University faculty member has been awarded a three-year, $426,000 grant by the National Institutes of Health to continue her lung cancer research.”

Patient's wish was to help out others
“When time was running out for Jill Paolucci, she and her family made an unselfish decision. Instead of receiving flowers and gifts during the final days of her fight against lung cancer, Jill received donations that would be used to help other families facing illness.”

Medical Specialists Creates Program in Response to National Cancer Institute Research Results
Munster, IN – “As a result of new medical research conducted by the National Cancer Institute and published in the New England Journal of Medicine, Medical Specialists recently launched a lung cancer screening program utilizing a new screening process.”

Adult Lungs Can Sprout New Growth
“The lungs may have greater capacity for regeneration in adults than thought, according to a case report of new growth after lung cancer resection.”

Dangers and Stigma of Smoking Have Helped Snuff Lung Cancer's Lethal Toll -- But Still Not Enough
“If you've ever watched the television series Mad Men, you've probably noticed how its main characters chain smoke like it's an Olympic sport. The show's dapper lead man, advertising executive Don Draper, is rarely without a cigarette in hand as he maneuvers through Madison Avenue of the 1960s. Smoking, of course, was a sign of the times -- a cool fashion, whether you were a housewife, a hippie or a high-society ad man.”

MSU nursing researcher’s Wii-Fit program helps lung cancer patients reduce fatigue
“With the support of a $379,741 grant from the National Cancer Institute and the Nintendo Wii game system, nursing researcher Amy Hoffman aims to help lung cancer patients reduce fatigue and get more exercise as they transition from the hospital to the home after surgery.”

Week Ending July 15, 2012

Surfing and Cycling With Stage 4 Lung Cancer
“Physicians at the University of Colorado Hospital are finding startling success with medications that are made to match the genes of a particular lung cancer. The new strategy means the drugs work only on certain patients – but they can work really well.”

New screening, drugs, surgical procedures aids fight against lung cancer
One out of three cancer deaths stems from lung cancer, but strides are being made in better screenings and treatments.

“Robots, GPS and earlier screenings are the latest high-tech salvo in the war against lung cancer.”

Golf tourney to help cancer victim
“Until succumbing to lung cancer in 2010, Robert Williams used to love to golf with his buddies in Tarboro.”

OMHS launching CT screening for lung cancer
KY- “Owensboro Medical Health System is now offering screening for lung cancer that includes a short risk assessment and a low-dose CT scan. The program is fashioned after the National Lung Screening Trial (NLST)—a seven-year study that showed a 20 percent reduction in lung cancer deaths with low-dose CT (as compared to chest X-ray). The study’s findings are significant because they indicate clear evidence of considerable reduction in death with a CT screening test in a randomized, controlled trial.”

Roanoke, Lynchburg to take part in national cancer prevention study
ROANOKE, VA -- “A major cancer study is looking for partcipants from the Roanoke and Lynchburg areas.”

Lung cancer discovery confirms drug target's potential
“A protein called Rac1 plays a key role in the development and spread of lung cancer, according to a research group in the US.”

OncoGenex Announces Clinical Development Plans for Custirsen in Non-Small Cell Lung Cancer
A Phase 3 Clinical Trial of Custirsen in Combination with Docetaxel as Second-Line Treatment in Patients with Non-Small Cell Lung Cancer to be Initiated Later this Year

“OncoGenex Pharmaceuticals, Inc. announced today an update on the clinical development program for custirsen and details on plans to initiate a Phase 3 clinical trial in non-small cell lung cancer (NSCLC).The trial, planned to begin enrollment later this year, will evaluate the potential survival benefit of combining custirsen with docetaxel, a standard second-line chemotherapy treatment used in patients who have progressed after initial, or first-line, treatment has failed.”

Memphis researcher gets $3 million for lung cancer study
“A Memphis doctor will lead a five-year study in the Mid-South to possibly improve lung cancer surgery survivor rates with an already proven testing process he helped developed here.”


Week Ending July 8, 2012

Exhibit captures trials of cancer on canvas
PEORIA — “The turbulent feelings associated with cancer treatment take form in "Lilly Oncology On Canvas Art Exhibition," which opens this week.”

Irish Cancer Society claims tobacco industry is targeting women
“The Irish Cancer Society has claimed the tobacco industry is aggressively targeting women and girls in the hope of recruiting more smokers.”

Nurse highlights the need for awareness
“A cancer nurse has highlighted the vital need to raise awareness of the persistent dangers of asbestos.”

Improving treatments for lung cancers: New targets tankyrase and wnt
“Funded in part by Uniting Against Lung Cancer, Dr. James DeGregori (University of Colorado, Denver) and collaborators have identified new targets to help improve patient responses to EGFR-targeted therapy, such as erlotinib (Tarceva) and gefitinib (Iressa).”

Nab-Paclitaxel Shows Promise in Advanced Lung Cancer
“The administration of nab-paclitaxel plus carboplatin results in a significantly higher overall response rate (ORR) than conventional solvent-based paclitaxel with carboplatin in previously untreated patients with advanced non–small cell lung cancer (NSCLC), according to the results of a phase III study. NSCLC is the number one cause of cancer-related death in the United States, with only 1% of patients with stage IV disease remaining alive at 5 years, the authors wrote.”

Cerulean reaches two milestones with lead compound
“Cerulean Pharma Inc. in Cambridge announced that it hit two milestones regarding trials of its lead drug candidate, CRLX101, in separate studies aimed at treating non-small cell lung cancer (NSCLC) and metastatic renal cell carcinoma (mRCC).”

UTMB introduces lung cancer screening program
GALVESTON — “Just a little more than a year ago, the New England Journal of Medicine published a study that showed lung cancer deaths could be significantly reduced when patients with heavy smoking histories but no symptoms received low-dose CT chest scans once a year during a three-year period. The study showed a 20 percent decrease in mortality in patients who received the CT scans compared to those who received chest X-rays.”

Week Ending July 1, 2012

Secrets of Lung Cancer Drug Resistance Revealed
“People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return -- it's a question of when. And for far too many, it happens far too soon.”

Women’s lung cancer deaths up in parts of US: study
“Lung cancer rates have been falling across the United States over the past decade, but deaths from the disease are steady or rising among middle-aged women in the South and Midwest, according to a study based on more than one million women.”

Diarrhea Less Severe With Molecularly Targeted Agents Than With Standard Chemotherapy
“It is well known that chemotherapy-induced diarrhea can increase morbidity and mortality and have a negative influence on treatment outcomes and quality of life. Further, it can lead to dose reductions and alterations in the therapeutic regimen. Much less is known about molecularly targeted agents and diarrhea, but recent evidence shows that some of these newer therapies can cause diarrhea.”

Cancer survivor turns effort toward teaching awareness
Gail Orcutt's awareness efforts were spurred by personal battle against lung cancer

“For Gail Orcutt, overcoming cancer was just the first step in a much bigger battle against one of the most overlooked threats and leading causes of lung cancer: radon exposure.”

Screenings can test for lung cancer
“Q: I was a smoker. I am worried about my risk of lung cancer. Is there a test to screen for lung cancer?
A: Yes. The results of a large, nationwide study conducted by the National Cancer Institute were published within the past year in The New England Journal of Medicine. More than 53,000 individuals were enrolled beginning in 2002. Thirty-four university medical centers participated.”

AATS Calls for Broader Lung Cancer Screening Guidelines
“Lung cancer screening guidelines should be expanded, according to a multispecialty task force established by the American Association for Thoracic Surgery. The recommendations were published last week in the online issue of the Journal of Thoracic and Cardiovascular Surgery.”


Week Ending June 25, 2012

Rhode Island Medical Imaging Announces Out-Patient Lung Cancer Screening Program
“Rhode Island Medical Imaging (RIMI) is pleased to announce the first comprehensive out-patient lung cancer screening program available in the state of Rhode Island. Highly publicized results from the National Lung Screening Trial (NLST) indicate that lung cancer screenings can detect lung cancers with computed tomography (CT) early enough to reduce lung cancer death rates by about 20%.”

Sisters share fight against cancer
Honorary survivors prepare for Relay for Life

“One might think two sisters who have been diagnosed with cancer, as well as both of their parents, would be thinking - "Why us?"”

Screening Recommendations Updated for Lung Cancer Survivors, Former Smokers
A new task force recommends that lung cancer survivors get yearly screenings for the disease five years longer.

“Long-term lung cancer survivors up to age 79 should be screened for the disease annually, according to a new task force.”

Chris Draft pushes for lung cancer death decrease, in honor of late wife
“Linebacker Chris Draft tackled tough for several NFL teams—and played to win. But, when the Redskins released him in 2010, he faced an opponent he couldn’t beat.”

MUSC gets $2 million to study lung cancer
“The Medical University of South Carolina in Charleston has received an almost $2 million grant to study lung cancer treatment in blacks.”

Researchers Work To Develop Simple Test
ST. LOUIS , MO (KTVI) – “Researchers are developing a simple test for lung cancer and all you have to do is breath into a tube.”

Pfizer says lung cancer drug meets study goal
“Pfizer Inc. said Tuesday its lung cancer drug Xalkori helped lung cancer patients who had previously been treated for the disease.”

Week Ending June 18, 2012

Stereotactic ablative radiotherapy benefits stage I non-small cell lung cancer patients
“Until recently, many elderly patients with stage I non-small cell lung cancer were left untreated because treatment may not improve their quality of life. However, stereotactic ablative radiotherapy (SABR) has become one of the standards of treatment for these patients. The outpatient treatment given over a two-week period allows frail patients to undergo the treatment.”

W.H.O. Declares Diesel Fumes Cause Lung Cancer
“Diesel fumes cause lung cancer, the World Health Organization declared Tuesday, and experts said they were more carcinogenic than secondhand cigarette smoke.”

ZIOPHARM Oncology Announces Dosing of First Patient in Phase 3 Study of Palifosfamide for the Treatment of Small Cell Lung Cancer
“ZIOPHARM Oncology, Inc., a biopharmaceutical company focused on the development and commercialization of new cancer therapies, today announced that the first patient has been dosed in the MATISSE study (Multicenter Adaptive Trial Investigating Small cell lung cancer Survival Endpoints), a pivotal Phase 3 multi-center, open-label, adaptive, randomized study of palifosfamide for the treatment of small cell lung cancer. ZIOPHARM has also recently announced the completion of enrollment in its Phase 3 study of palifosfamide in combination with doxorubicin for the treatment of metastatic soft tissue sarcoma in the front-line setting (PICASSO 3).”

At-Home Test to Prevent Lung Cancer
“Radon, a naturally occurring and odorless gas, can get trapped in your home or lungs and cause significant illness. People in the Valley got free test kits Monday to help prevent this.”

ASCO: Erlotinib Worse Than Docetaxel for Wild-Type EGFR NSCLC
“In patients with advanced non–small-cell lung cancer (NSCLC) and without any mutation in the EGFR gene, docetaxel(Drug information on docetaxel) provides significantly improved progression-free survival compared to erlotinib (Tarceva), according to a phase III randomized trial. And importantly, a common gene mutation was not seen to play any prognostic role in these patients.”

ASCO: Pemetrexed Maintenance Therapy Better Than Placebo for Advanced NSCLC
“The final survival results from the PARAMOUNT study in nonsquamous non–small-cell lung cancer confirmed that continuation maintenance therapy with pemetrexed(Drug information on pemetrexed) (Alimta) improves survival compared with placebo. The investigators say these results warrant a change in the treatment paradigm for patients in this setting.”

ASCO: Addition of Cetuximab to Pemetrexed Fails to Improve Survival in Advanced NSCLC
“The idea of adding the targeted EGFR inhibitor cetuximab(Drug information on cetuximab) (Erbitux) to standard chemotherapy took a hit, as results from the SELECT phase III trial showed no improvement in efficacy when cetuximab was combined with pemetrexed(Drug information on pemetrexed) in patients with recurrent or progressive non–small-cell lung cancer (NSCLC).”

Week Ending June 10, 2012

Doublet Regimen Tested for Salvage Therapy in NSCLC
“A doublet regimen of mitomycin C and irinotecan can provoke roughly a 20% response rate when it is used as salvage therapy in patients with advanced non-small cell lung cancer (NSCLC), according to a study from Texas researchers.”

ASCO: Zaltrap Has Potential in Refractory SCLC
“A novel agent that "traps" vascular endothelial growth factor (VEGF) slows progression of platinum-resistant small cell lung cancer (SCLC), a phase II trial showed.”

Cancer breathalyzer: Researchers developing breath test for possible diagnosis of lung and breast cancers
“A breath test designed to detect established lung cancer in humans showed promising results in a study conducted by researchers at the Georgia Institute of Technology and the Winship Cancer Institute of Emory University. The researchers presented their results June 2 at the annual American Society of Clinical Oncology (ASCO) meeting in Chicago.”

Celgene Advances ABRAXANE(R) (nab-paclitaxel) Development in Difficult-to-Treat Cancers
Phase III randomized clinical study in metastatic pancreatic cancer completed enrollment

“Celgene International Sarl, a subsidiary of Celgene Corporation today announced a series of milestones related to the development of ABRAXANE (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) in metastatic pancreatic cancer, advanced non-small cell lung cancer, metastatic breast cancer and metastatic melanoma.”

ASCO: Starting Radiation Later OK in SCLC
“Radiation for small-cell lung cancer (SCLC) can safely be delayed until after the first cycles of chemotherapy without hurting outcomes, a randomized trial determined.”

Lung Cancer Study Showed Encouraging Results For ALIMTA-based Regimens And Full-dose Radiation
Phase II trial results support ongoing registration study, PROCLAIM, which is currently enrolling patients

“Eli Lilly and Company announced results of a Phase II trial evaluating ALIMTA® (pemetrexed for injection) in combination with a platinum chemotherapy and radiation for patients with locally advanced non-small cell lung cancer (NSCLC). The findings will be presented at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Ill. on June 4, 2012.”

Week Ending June 4, 2012

New Drug Helps Immune System Fight Cancer, Study Says
A study conducted in part by researchers at the Yale School of Medicine suggests that a new drug that bolsters the immune system can shrink tumors in certain cancers — including lung cancer, which has been resistant to treatment

Tumors shrank by at least 30 percent in 28 percent of the melanoma patients; a slightly smaller percentage of renal cancer patients had similar reductions in tumors. And 18 percent of the lung cancer patients had tumor reductions of 30 percent or more.

Cough up now for early advice on cancer
Be Clear on Cancer aims to increase awareness of the key symptoms of lung cancer, and improve earlier diagnosis.

New data reveals that only one in 10 people know that a cough lasting three weeks or more could be a symptom of lung cancer, and if dealt with early, could save their life.

New Phase II Data on Investigational Drug NGR-hTNF Presented at ASCO
First data of a randomised 1st-line study indicate an extension of survival in squamous cell lung cancer Combination with doxorubicin induces long-term responses in small-cell lung cancer and in ovarian cancer In mesothelioma, 3-year follow-up data confirm the benefit of dose intensification and validate the design of the ongoing pivotal Phase III study

"In the last few days, we presented at ASCO an overview of our extensive effort in the clinical development of NGR-hTNF, our molecule selectively active on the tumour vasculature, currently the only drug under investigation in Phase III in recurrent pleural mesothelioma. I would like to emphasize that the analysis of long-term results of phase II studies presented this year confirms the extension of survival as the most common clinical benefit observed in these studies. It is of importance that this finding is also confirmed by the primary analysis of patients with squamous cell histology enrolled in the first randomized study of NGR-hTNF presently ongoing in non-small cell lung carcinoma. Another important novelty emerged from these studies and in particular from our efforts to identify potential predictors of response, is the correlation among chills during drug infusion, lymphocyte counts and a prolonged clinical benefit, consistently with the hypothesized mechanism of action of NGR-hTNF."

Boehringer plans to challenge lung cancer drugs
German drug company Boehringer Ingelheim said on Monday it would test its experimental lung cancer drug directly against AstraZeneca's Iressa and Roche's Tarceva pill, after it showed promise in a late-stage drug trial.

A study showed Boehringer's afatinib drug prolonged the time lung cancer patients survived without a worsening of their condition by 4.2 months on average when compared with a control group on standard chemotherapy.

Cancer treatments grow more high-tech: ‘Smart bomb’ drugs, immune boosters are seeing success
New research shows a sharp escalation in the weapons race against cancer, with several high-tech approaches long dreamed of but not possible or successful until now.

These are two-punch weapons that combine substances called antibodies, which bond with specific cancer cells, and toxins that are too potent to be given by themselves. A chemical link holds them together until they attach to a tumor cell, releasing the poison inside it and killing the cell.


Week Ending May 21, 2012

Lung cancer CT scans: Just for older heavy smokers
New lung cancer screening guidelines from three medical groups recommend annual scans but only for an older group of current or former heavy smokers.

The advice applies only to those aged 55 to 74. The risks of screening younger or older smokers or nonsmokers outweigh any benefits, according to the guidelines.
About 8 million Americans would be eligible for screening under the new criteria, and if all of them got the scans, about 4,000 lung cancer deaths per year could be prevented, said Dr. Peter Bach of Memorial Sloan-Kettering Cancer Center in New York.

Peregrine Announces Positive Top-Line Data From Randomized, Double-Blind Bavituximab Phase II Trial in Second-Line Non-Small Cell Lung Cancer
Bavituximab Plus Chemotherapy Demonstrates Doubling of Overall Response Rates Versus Chemotherapy Alone; 50% Improvement in Progression-Free Survival and Overall Survival Trends Support Phase III Development

"After working on over 17 drug approvals, it is data like this that continues to energize and excite me. These robust data will be important in discussions with the FDA regarding advancing bavituximab's clinical development in second-line non-small cell lung cancer," said Robert Garnick, PhD, head of regulatory affairs at Peregrine. "We look forward to working closely with the FDA to identify the most efficient path toward commercialization for this promising candidate in this indication where new therapies are desperately needed."

Stopping cell migration may help block fibrosis and the spread of cancer
Discoveries by a Yale-led team of scientists could lead the way for development of new therapies for treating fibrosis and tumor metastasis.

Senior author Dianqing (Dan) Wu, professor of pharmacology and vascular biology at Yale School of Medicine and member of Yale Cancer Center, explained, “Our ability to block the pathway provides a potential therapeutic target for treating pulmonary fibrosis, a very serious disease that lacks effective treatments, and other types of fibrosis. Because cancer cells, particularly melanoma and lung cancer cells containing activated BRAF genetic mutations, can use this signaling pathway to migrate, blocking this pathway could also prevent metastasis of these cancers.”

Momentum Continues To Build For Federal Plan Of Action For Lung Cancer -- Advocate Voices Play Leading Role
Over a Dozen New Members of Congress Added to the Lung Cancer Mortality Reduction Act

The Lung Cancer Mortality Reduction Act, S.752 and H.R.1394 respectively, is the first-ever legislation calling for a coordinated and comprehensive federal plan to address all aspects of lung cancer.

Pfizer drug shows promise in lung cancer-study
An experimental lung cancer pill being developed by Pfizer Inc showed promise in delaying worsening of the disease, according to preliminary results from a midstage study.

Dacomitinib inhibits a variety of proteins that play a role in cell division and proliferation, including EGFR, HER-1, HER-2 and HER-4, that can lead to progression of cancer. Over expression of HER has been associated with late stage cancers, including breast, lung, gastric and colorectal cancers.

Week Ending May 13, 2012

More cancer patients seek treatment in Las Vegas
“It was the diagnosis Paul Bodner never thought he would receive.

The longtime Las Vegan spent his 40-plus-year career in the health care industry, as a hospital CEO and later a health care consultant. He said he had always adhered to "a totally healthy lifestyle - eating right, exercising, (doing) all of the right things."”

Striking photo a tribute to selfless mother
Two grown children honour their mom in Journal contest
EDMONTON — “With a striking photo she made with her son, Kathy Hogan is staring terminal cancer in the face.”

New Research Shows Minimally Invasive, Video-Assisted Thorascopic Lobectomies
“In a retrospective analysis using the Premier hospital database, the minimally-invasive approach of video-assisted thorascopic surgery lobectomies for lung cancer indications show both clinical and economic advantages compared to open thoracotomy for lobectomy.”

Lung Cancer Alliance, Legacy And Prevent Cancer Foundation Protest Delays In Government Review Of CT Screening Urge HHS Secretary Sebelius To Intervene
WASHINGTON, May 9, 2012 -- /PRNewswire-USNewswire/ -- “Lung Cancer Alliance, Legacy and Prevention Cancer Foundation protested "unconscionable delay" in the federal government's review of CT screening for those at high risk for the early detection of lung cancer and sent a letter urging Secretary of Health and Human Services (HHS) Kathleen Sebelius to intervene.”

Week Ending May 6, 2012

Bad cough is lung cancer's main symptom, highlights campaign
It is Britain’s most lethal cancer but most people do not know the principal symptom that may indicate its presence.

National Lung Cancer Partnership, Medical Centers Collaborate to Provide Tumor Testing
The National Lung Cancer Partnership is collaborating with 14 top cancer centers across the country to sustain the Lung Cancer Mutation Consortium, the largest-ever effort to promote molecular tumor testing for lung cancer patients.

Study finds that patient education videos viewed before an operation may benefit patients
A patient education process may provide an antidote to the emotional and physical difficulties that lung cancer patients face before and after an operation, according to a new study published in the May issue of the Journal of the American College of Surgeons. Specifically, researchers report that lung procedure patients who watched a 30-minute preparation video reported less anxiety about the procedure, less physical pain after the operation, and higher rates of overall satisfaction with the operative experience.

Women who don't smoke can still get lung cancer
A pesky cough, that's all.

The last thing on Michaelle Gall's mind was late-stage lung cancer. She had just turned 41. She was a physically fit mom and nonsmoker, except for the rare social occasions when some friends might light up.

Older Lung Cancer Patients Less Likely to Be Treated
(HealthDay News) -- A study of seniors with non-small cell lung cancer found that older patients are less likely to receive treatment than younger patients, regardless of their overall health and prognosis.

Lung Cancer - Even If You Can't Prevent It, There May Be A Better Way To Kill It
Among cancer deaths worldwide, lung cancer is the leader.

It isn't just the tumor cells, the growth of blood vessels controls tumors development and blood vessel growth is controlled by several signalling molecules. Scientists have discovered a molecule, phosphodiesterase PDE4, that plays a key role in this process and they have succeeded in reducing tumor growth in their experiments by blocking it.

Advanced Radiotherapy Linked To Improved Survival Rates Among Elderly Lung Cancer Patients
The latest issue of the journal Annals of Oncology reports that a major new study by one of the country's leading cancer centers, the VU University Medical Center (VUMC) in Amsterdam has revealed that widespread use of advanced radiotherapy techniques in the Netherlands has resulted in improved survival rates amongst elderly lung cancer patients.

Trial to assess lung cancer screening with combined CT, blood test
National Jewish Health in Denver is launching a lung cancer screening trial that will combine a CT chest scan and the EarlyCDT-Lung blood test, and will seek to build on recent research demonstrating that CT screening alone can reduce lung cancer mortality.

Geron Completes Enrollment in Phase 2 Clinical Trial of Imetelstat in Non-Small Cell Lung Cancer
Geron Corporation today announced that the company has completed planned enrollment of its randomized Phase 2 clinical trial of imetelstat, a telomerase inhibitor, as maintenance therapy following platinum-based induction therapy for patients with advanced non-small cell lung cancer (NSCLC).

Light Smoking Dramatically Increases Risk of Lung Cancer
It is a classic study performed in Oslo and it holds up as a landmark report. The end result of the study is smokers who believe a few cigarettes a day don’t do any harm will need to think again.

American Lung Association Provides Guidance on Lung Cancer Screening
“The American Lung Association announced today that it has released new interim guidelines to assist physicians, their patients and the public in their discussions about lung cancer screening. Lung cancer is the leading cause of cancer death for both men and women in the United States; having a five-year survival rate of only 15 percent. Recent research from the National Cancer Institute National Lung Cancer Screening Trial (NLST) found that low-dose computed tomography (CT) is a promising clinical strategy for the detection of pre-symptomatic lung cancer in individuals at the highest risk for lung cancer, reducing deaths by 20 percent compared to chest X-ray.”

Is Cancer-Causing Radon Prevention Being Neglected by State Legislators?
Could more be done to prevent cancer deaths in Iowa due to exposure to Radon? How is this tied to legislative funding?

“Radon, typically found in the basement of a house, kills 400 Iowans a year, but the state health department cannot carry out a state law designed to help protect residents from the deadly gas because it doesn’t have any staff to do so.”

Gene Critical to Development and Spread of Lung Cancer Identified
“A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida. Their study suggests other forms of cancer may also be driven by this gene, matrix metalloproteinase-10 (MMP-10).”

Lung Cancer Fundraiser Diagnosed with Disease, Community Rallies
More than 600 people are expected at the Breathe Deep Deerfield inaugural event, which has already raised $88,000.

The fight against lung cancer has always been personal for Jill Feldman of Deerfield. Before she was 30, she had lost her mother, father, aunt and two grandparents to the disease. Looking for a way to fight, she joined the Chicago-based organization LUNGevity when it was founded by seven cancer patients in 2001.

Aspirin tied to lower lung cancer risk in women: study
(Reuters) - Women who took aspirin at least a couple of times a week had a much lower risk of developing lung cancer, whether or not they ever smoked, according to a study of more than a thousand Asian women.


Week Ending April 29, 2012

American Lung Association Provides Guidance on Lung Cancer Screening
“The American Lung Association announced today that it has released new interim guidelines to assist physicians, their patients and the public in their discussions about lung cancer screening. Lung cancer is the leading cause of cancer death for both men and women in the United States; having a five-year survival rate of only 15 percent. Recent research from the National Cancer Institute National Lung Cancer Screening Trial (NLST) found that low-dose computed tomography (CT) is a promising clinical strategy for the detection of pre-symptomatic lung cancer in individuals at the highest risk for lung cancer, reducing deaths by 20 percent compared to chest X-ray.”

Is Cancer-Causing Radon Prevention Being Neglected by State Legislators?
Could more be done to prevent cancer deaths in Iowa due to exposure to Radon? How is this tied to legislative funding?

“Radon, typically found in the basement of a house, kills 400 Iowans a year, but the state health department cannot carry out a state law designed to help protect residents from the deadly gas because it doesn’t have any staff to do so.”

Gene Critical to Development and Spread of Lung Cancer Identified
“A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida. Their study suggests other forms of cancer may also be driven by this gene, matrix metalloproteinase-10 (MMP-10).”

Lung Cancer Fundraiser Diagnosed with Disease, Community Rallies
More than 600 people are expected at the Breathe Deep Deerfield inaugural event, which has already raised $88,000.

The fight against lung cancer has always been personal for Jill Feldman of Deerfield. Before she was 30, she had lost her mother, father, aunt and two grandparents to the disease. Looking for a way to fight, she joined the Chicago-based organization LUNGevity when it was founded by seven cancer patients in 2001.

Aspirin tied to lower lung cancer risk in women: study
(Reuters) - Women who took aspirin at least a couple of times a week had a much lower risk of developing lung cancer, whether or not they ever smoked, according to a study of more than a thousand Asian women.

Week Ending April 23, 2012

Targeted Drug Active in Resistant NSCLC
Outcomes in treatment-resistant non-small cell lung cancer (NSCLC) improved modestly with the second-generation tyrosine kinase inhibitor (TKI) dacomitinib, according to subgroup analyses of two clinical trials.

In a study of second- and third-line regimens, treatment with dacomitinib or erlotinib led to a median progression-free survival of 8 to 9 weeks among patients with nonadenocarcinoma NSCLC. However, survival curves continued to separate after the median, suggesting a potential benefit for dacomitinib with continued therapy, Fiona Blackhall, MD, said here at the European Lung Cancer Conference.

VeriStrat test may be useful for NSCLC clinical decision-making
Results showed that the VeriStrat test was able to identify patients likely to have better and worse survival outcomes when treated with the combination therapy.

"These data represent the third study in which we have shown that VeriStrat classification correlates with survival outcomes in lung cancer patients treated with bevacizumab plus erlotinib, " commented David Brunel, CEO of Biodesix. "Although additional data is needed, this study supports the view that VeriStrat may be useful in identifying lung cancer patients that could benefit from the combination of bevacizumab and erlotinib, which is regarded as less toxic than traditional chemotherapy."

Opioids may spur tumor growth
Although opioid-based painkillers are a standard treatment for relieving cancer pain, they may actually contribute to the progression of the disease, as two recent studies published in the journal Anesthesiology indicate.

The investigators found that overexpression of µ-opioid receptors in a human non-small cell lung cancer cell line increased tumor cell proliferation, migration, and invasion, all of which are measures of tumor growth and metastasis. When transplanted in mice, human lung cancer cells with additional copies of the opioid receptor grew more than twice as quickly as did tumor cells without the extra receptors. In addition, the cells with the extra opioid receptors were 20 times more likely to metastasize to distant sites.

Hispanic lung cancer patients tend to live longer than blacks and whites
Compared with white patients, Hispanic patients had a 15 percent lower risk of dying during the years of the study, whether they were born in the United States or not. "This is important because it shows that our findings are indicative of the Hispanic population in general and not specific to specific groups of Hispanics," said Saeed. Black patients were slightly more likely to die than whites. Also, Hispanics were more likely to develop a lung cancer type called bronchioalveolar carcinoma that is not as serious or life-threatening as other types.

Possible New Cancer Treatment Identified
New research findings show how it may be possible to render cancer tumours harmless without affecting the other cells and tissues in the body. The findings apply to cancers including breast, lung and bowel cancer. The study was carried out at Lund University in Sweden.

Researchers at Lund University have now found a connection between two proteins that in different ways control cell division and the possibilities for a cancer tumour to develop. The retinoblastoma protein obstructs cell division and is absent in most types of cancer tumour. The new findings show that its absence leads to an increase in another protein, gamma-tubulin, which, when present in high levels, encourages the development of cancer tumours. However, if gamma-tubulin is blocked, the tumour cells die while the healthy cells survive.

Big rise in lung cancer cases
WOMEN are increasingly more likely to be diagnosed with lung cancer than men in South Yorkshire.

Statistics released by the Cancer Research UK show that, although there are still more cases of men being diagnosed, the rates for women are increasing, whereas male diagnosis rates are falling.

Week Ending April 15, 2012

Lung cancer cases 'have increased rapidly in the UK'
“The number of lung cancer cases in the UK has risen over the past three decades, with the popularity of smoking in the 1960s being linked to the increase.”

Lung Cancer Screenings Deemed 'a Good Value'
A non-invasive scan that makes 3D pictures of the lungs could reduce lung cancer deaths for a relatively low cost per life saved, a new study says. Annual low-dose CT scans of middle-aged Americans who have smoked the equivalent of a pack of cigarettes every day for 30 years would cost each insured American an extra 76 cents a month.

“Screening longtime tobacco users for lung cancer would be less costly than the widely accepted practice of screening for breast, cervical and colorectal cancers and would reduce the death toll of lung cancer by an estimated 15,000 lives a year, according to a study released this week that is likely to ignite debate on expanding health-care coverage for smokers.”

Lung cancer stigma interferes with care
10-20% of lung cancer patients never smoked but all are judged harshly, nurse says

“Canadians with lung cancer face a barrage of negative attitudes from caregivers, friends and relatives that interfere with caring behaviour, a cancer patient advocacy group says.”

Aspirin and Lung Cancer Risk in Asian Women
“There has been a lot in the news about the role aspirin may play in cancer prevention. Many studies have looked to see if there is a benefit in preventing colon cancer.”

Possible new Lung Cancer Chemo Combo
Non-small cell lung cancer responds to chemotherapy combination

“Scientists continue to search for next-step treatment options for people living with lung cancer. A combination of chemotherapy agents may be an alternative for some folks.”

Patients Sought for Early-Stage Lung Cancer Clinical Study
Patients with breathing problems and early-stage lung cancer are sought by Barnes-Jewish and Washington University.

“The Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is seeking patients for a clinical study to determine the best treatment for patients with early-stage lung cancer who also have breathing problems.”

Week Ending April 8, 2012

Back to work after radical cancer treatment
Only if her lung cancer spread would Cassandra Jardine be allowed to join a trial of a new gene therapy.

“Four weeks ago, I suddenly felt sick. It was a moment of pure joy. After seven months, one week and 10 hours, the waiting was over.”

HIV Contributes to Lung Cancer Risk, but Smoking Matters Most
“HIV infection increases the risk of developing lung cancer by about 70 percent, according to a study conducted by U.S. Department of Veterans Affairs researchers and published online ahead of print by the journal AIDS. However, the researchers note, it is smoking among people living with HIV that poses the greatest risk of developing lung cancer.”

Gulf Coast Medical introduces area's first cancer-screening tool
PANAMA CITY — “Early detection of lung cancer can have a dramatic impact on reducing mortality rates and Gulf Coast Medical Center introduced Thursday the area’s first and only lung cancer screening.”

Most physicians ordered lung cancer screening tests for asymptomatic patients
“Primary care physicians frequently order lung cancer screening tests for asymptomatic patients, contrary to current practice guidelines, according to study results published in Annals of Family Medicine.”

How to Encourage Radon Testing to Prevent Lung Cancer?
“Checking our homes for radon is one of the easiest things people can do to prevent cancer. It doesn't take willpower. It's relatively cheap. You only have to do it once. And if the level is abnormal and you fix it, you've successfully eliminated your exposure to the second leading cause of lung cancer. And the leading cause in non-smokers.”

Early Study Finds Some Promise for Lung Cancer Vaccine
“A new therapeutic vaccine appears to lengthen the lives of patients with a certain type of lung cancer, according to results of a small phase 2 trial.”

Link Between Estrogen and Tobacco Smoke: Estrogen May Help Promote Lung Cancer
ScienceDaily (Apr. 3, 2012) — “The hormone estrogen may help promote lung cancer -- including compounding the effects of tobacco smoke on the disease -- pointing towards potential new therapies that target the hormone metabolism, according to new research presented at the AACR Annual Meeting 2012 on April 3 by scientists at Fox Chase Cancer Center in Philadelphia.”

Lung cancer on the rise among non-smokers
“Since new and graphic anti-smoking ads debuted, calls to a toll-free number to help people quit cigarettes have doubled, according to the Centers for Disease Control.”

Lilly Targets Faulty c-MET Receptor in Cancer Research Studies Presented Today at AACR Meeting
Studies provided basis for ongoing Phase I, II studies in gastric, other cancers

“Eli Lilly and Company today announced results of three preclinical studies focused on c-MET, a receptor tyrosine kinase that, when it functions normally, plays a key role in transmitting signals within a cell. Abnormalities in c-MET function and signaling have been found in many types of cancer including lung, breast, prostate, gastric, esophageal and renal cancers.”

Week Ending April 1, 2012

Quality of life tied to lung cancer survival:study
(Reuters) - The way lung cancer patients feel around the time they're diagnosed may be related to how long they survive - even after taking into account objective measures of the disease, according to a U.S. study.

“Researchers, whose results were published in the Journal of Clinical Oncology, found that newly-diagnosed lung cancer patients who rated their quality of life higher generally lived longer with the disease, typically surviving nearly six years, versus less than two years among patients who'd reported a poor quality of life.”

Cancer docs often don't notice family discord
(Reuters Health) - Doctors caring for lung cancer patients are often unaware when patients and their caregivers disagree about the best course of treatment, according to a new study.

“"Unless you're doing an assessment of conflict, which oncologists do not do, I'm not surprised that they wouldn't perceive it," said Betty Kramer, who studies aging and family caregiving at the University of Wisconsin-Madison School of Social Work but wasn't involved in this research.”

Presurgical Chemotherapy for Early Stage Lung Cancer
“Surgery is considered by many to be the "treatment of choice" for people with early stage lung cancer. Through removal of the tumor, surgery may offer the chance for long term cure from the disease.”

Bucket list: Vietnam vet with cancer to ride motorcycle across U.S.
PLANO – “A 58-year-old cancer patient from Plano is about to take the ride of his life.”

Lung Cancers Detected by CT Screening Grow at Same Rate as Those Found Through Traditional Methods
“A new study led by researchers at Mount Sinai School of Medicine indicates that CT scans are more effective than traditional lung cancer detection methods at identifying aggressive lung cancers in their most treatable stages.”

ImmunoGen announces Phase II lung cancer trial, T-DM1 showing promise
“ImmunoGen announced Friday that it has launched its phase 2 testing of drug candidate lorvotuzumab mertansine (IMGN901) for the treatment of small-cell lung cancer (SCSC).”

Department of Defense Lung Cancer Research Program Funding Opportunities for Fiscal Year 2012
“The Fiscal Year 2012 (FY12) Defense Appropriations Act provides $10.2 Million (M) to the Department of Defense Lung Cancer Research Program’s (LCRP) to support innovative, high-impact lung cancer research. The LCRP is administered by the US Army Medical Research and Materiel Command (USAMRMC) through the Office of the Congressionally Directed Medical Research Programs (CDMRP).”

Highlighting lung cancer awareness
State Health Registry issues Cancer in Iowa 2012 report

“The latest annual report on cancer in Iowa estimates 6,400 Iowans will die from cancer and 17,500 new cancers will be diagnosed this year, according to the Cancer in Iowa: 2012 report released today by the State Health Registry of Iowa, based in the University of Iowa College of Public Health.”

Lung cancer advances drive better prognosis
“Patricia Diamond has had a bit of luck in the timing of her misfortune.”

Radon level is high at governor's mansion
Kitzhaber's companion urges Oregonians to test their homes
“The governor’s mansion has higher-than-recommended levels of radon, a cancer-causing and radioactive gas.”

'Co-clinical trials' help focus lung cancer research
“A new form of scientific multitasking has enabled Dana-Farber Cancer Institute researchers and their colleagues to identify genetic markers that may indicate which lung cancer patients have the best chance of benefiting from a particular combination of drugs.”


Week Ending March 25, 2012

NCCN Reaffirms Lung Cancer Screening of Heavy Smokers
“The benefits of routine lung cancer screening in high-risk individuals outweigh the potential risks, according to members of a National Comprehensive Cancer Network guidelines panel that recommended low-dose helical CT screening of two high-risk groups.”

Lower Dosage CT-guided Lung Biopsy Protocol Maintains Quality, Minimizes Exposure
“New guidelines for CT-guided biopsies of lung nodules significantly reduce radiation exposure allowing individuals the benefit of the procedure, which may cut down on overall lung cancer deaths. This research is being presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco, Calif.”

Moffitt Cancer Center researchers link stigma to depression among lung cancer patients
“Studying the role of social stigma in depression for lung cancer patients, researchers at Moffitt Cancer Center in Tampa, Fla., have found that depression can be heightened by a lung cancer patient's sense of social rejection, internalized shame and social isolation. These factors may contribute to depression at rates higher than experienced by patients with other kinds of cancer.”

Nation's largest lung cancer-focused nonprofit receives 2012 CEB Community Investment Grant to help stop lung cancer
“LUNGevity Foundation is pleased to announce Corporate Executive Board (CEB), an Arlington, Va. based leading research and advisory services firm, as one of its 2012 National Sponsors. As a National Sponsor, CEB helps LUNGevity in its quest to fund life saving research for treatments and cures for the nation's number one cancer killer, providing resources and helping build a community for those impacted by the disease.”

Smoking and lung cancer: A deadly link
“As the vice chairman of research in the department of medicine at Mount Sinai School of Medicine, Dr. Juan Wisnivesky is a pulmonologist who specializes lung cancer research. This is the third column in a month-long series devoted to cancer.”

Pain Meds Could Be Linked To Tumor Growth
“Opioids, a type of molecule that includes painkillers like morphine, may stimulate tumor growth, according to two studies appearing in the latest issue of the journal Anesthesiology. The studies suggest that opioid painkillers may hamper recovery for cancer patients but could also lead to a new possible target for tumor-fighting drugs.”

Passive smokers beware: Second-hand smoke can also cause cancer
“Those who are of opinion that they are not at the risk of cancer, since they don't smoke, should be get alert as even being a passive smoker or getting exposed to secondhand smoke can make them susceptible to cancer. A key protein linked to cell function and regulation get stopped by cancer-causing agent present in gaseous phase of cigarette smoke, a new research led by Indian origin scientist has revealed.”

Week Ending March 18, 2012

Genetic Variation in East Asians Found to Explain Resistance to Cancer Drugs
ScienceDaily (Mar. 18, 2012) — “A multinational research team led by scientists at Duke-NUS Graduate Medical School has identified the reason why some patients fail to respond to some of the most successful cancer drugs.”

Anti-smoking efforts save 800,000 US lives
“Higher taxes on cigarettes, limits on selling to kids and campaigns to educate people on the dangers of smoking have saved nearly 800,000 lives, according to a US study released on March 14.”

Declines in smoking and lung cancer mortality in the U.S.
“Although changing smoking behaviors have had a major impact on lung cancer mortality in the U.S., the numbers of lung cancer deaths averted are only a small fraction of deaths that could have been avoided had all smoking ceased following the 1964 Surgeon General’s Report. Further efforts to control tobacco use are needed to decrease the impact of the disease, according to a study published in the Journal of the National Cancer Institute.”

Lung Cancer Alliance Comments on CDC's New Ad Campaign
“Today, Lung Cancer Alliance (LCA) said that the new anti-tobacco campaign just launched by the Centers for Disease Control and Prevention (CDC) is an important revitalization of the efforts to prevent young people from smoking and encourage all who do smoke to quit.”

Smokers to be screened for lung cancer in Scotland
Smokers are to be screened for lung cancer in Scotland, using a blood test that identifies if they are at a high risk of developing the disease.

The idea is to spot the cancer early enough to remove it surgically before it has spread - something that rarely happens at the moment.”

Panel of 10 serum protein biomarkers could help in lung cancer diagnosis
“A panel of serum biomarkers could help predict the level of lung cancer risk in high-risk patients, offering doctors an option before proceeding with a biopsy. Research presented in the April 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology shows that a panel of 10 serum protein biomarkers could help in the lung cancer diagnosis. The biomarkers include: prolactin, transthyretin, thrombospondin-1, E-selectin, C-C motif chemokine 5, macrophage migration inhibitory factor, plasminogen activator inhibitor-1, receptor tyrosine-protein kinase erbB-2, Cyfra 21.1 and serum amyloid A. Further work is necessary to validate these exciting results”

National Nutrition Month - Foods That Lower Lung Cancer Risk
“During National Nutrition Month we're hearing a lot about how to eat. But what if you have a special concern? What if you're worried about developing lung cancer?”

Week Ending March 11, 2012

Drug Resistance in Lung Cancer Treatment
Non small cell lung cancer treatment influenced by oncogenic EGFR protein mutations

“Some types of cancer treatment are on a molecular level, relying on interactions between growth receptor proteins on the cancer cells and drugs that target these specific receptor proteins.”

Report adds to debate over menthol cigarettes
“Food and Drug Administration scientist has found a lower risk of dying from lung cancer among menthol smokers compared to non-menthol smokers at ages 50 and over.”

New Aspirin Might Cure Cancer
“It has been recently revealed in a report that the development of a new form of aspirin is in processing. This shall be a novel and advanced form of the same, which shall be helpful in fighting breast, colon, pancreas, and blood and lung cancer.”

Cancer patients do well at US veterans' hospitals
(Reuters Health) – “Older men treated for cancer at Veterans Health Administration hospitals do just as well, if not better, than men covered by Medicare, a new study suggests.”

Utahns at high risk of lung cancer can be screened early
“A newspaper ad prompted 83-year-old Wanda Parkinson of Kearns to volunteer for a lung cancer study. Marcia Michael, a 75-year-old Holladay resident, talked her doctor into screening her for lung cancer after her sister was diagnosed with the disease.”

Get your Lung Cancer Matters tags here
ALBANY, GA – “Did you know that Lung Cancer kills more people than Breast, Prostate, and all others Cancers combined? Jackie Archer who lives in Atlanta plans to do something about it.”

CU Cancer Center aims to make progress against squamous cell lung cancer
“Recent advances in targeted cancer treatments greatly bolster the prognosis for many types of lung cancer, but according to a University of Colorado Cancer Center investigator, "practically nothing has improved in squamous cell lung cancer in the last decades."”

Week Ending March 4, 2012

Prostate, Colon, Lung Cancer Rates Down
“Cancer rates for lung, prostate and colon cancer has dropped significantly for men in the United States, according to the latest Cancer Facts & Figures report from the American Cancer Society.”

Report: Nurses can support patients with lung cancer
“Nurses should play a key role in alleviating concerns of patients newly diagnosed with lung cancer, leading to a better quality of life for those patients, according to a report.”

Lung cancer tragedy of the women targeted by cigarette adverts in post-war years.
More will die from lung cancer than any other form

“Women are paying a deadly price for being targeted by tobacco advertisers in the post-war years, health experts claimed yesterday.”

Robotic lung cancer surgery a first in Canada
“The robots are taking over - surgery, that is. Doctors at Toronto General Hospital who performed a Canadian first when they removed cancer and the lobe of a lung by means of robotic surgery in October say the ongoing success of the post-op - with the patient still cancer-free as of this week - paves the way for more surgeries of its kind.”

Drug may be near for cancer's companion condition cachexia
Cachexia is the muscle wasting and weight loss that often accompany cancer's effects. Two potential treatments that may boost muscle strength are in Phase 3 clinical trials.

“Bonnie Addario didn't even know there was a word for what was happening to her. As if lung cancer weren't bad enough, the 54-year-old had lost 30 pounds off her normally 130-pound frame. Her life was limited to her husband's Barcalounger, where she had to recline because she lacked the strength to sit up straight.”

Despite loss, former Falcon continues lung cancer campaign, fund-raising
“For years, organizations such as Lung Cancer Alliance and the National Cancer Institute at the National Institutes of Health have dedicated countless hours and millions of dollars to educate the public about lung cancer and new developments in detection and treatment. Yet as well-known as these entities are, their message often is overshadowed by other cancers, especially ones with higher survival rates such as breast cancer.”

Some with lung cancer get unhelpful radiation
(Reuters Health) – “Older adults who have surgery for a particular type of lung cancer often have radiation therapy afterward. But a new study suggests that the radiation typically does nothing to extend their lives.”

Vandetanib Doesn’t Up Survival in Non-Small-Cell Lung Cancer
“Vandetanib does not improve overall survival for patients who have received previous treatment for advanced non-small-cell lung cancer, according to a study published online Feb. 27 in the Journal of Clinical Oncology.”

Heavy exposure to diesel exhaust linked to lung cancer death in miners
“In a study of non-metal miners in the United States, federal government scientists reported that heavy exposure to diesel exhaust increased risk of death from lung cancer. The study was carried out by researchers from the National Cancer Institute (NCI), part of the National Institutes of Health, and the National Institute for Occupational Safety and Health (NIOSH), part of the Centers for Disease Control and Prevention, both parts of HHS. The results were distributed in two papers on March 2, 2012, from the Journal of the National Cancer Institute and they will be posted to the JNCI website on March 5, 2012.”


Week Ending February 26, 2012

Norwalk Hospital launches screening program
“Norwalk Hospital has launched a lung cancer-screening program based upon the findings of the National Lung Screening Trial (NLST) sponsored by the National Cancer Institute and the New England Journal of Medicine. The program is being led by Dr. James Bauman, radiologist with Norwalk Hospital and Norwalk Radiology and Mammography Center, and Dr. Stephen Winter, chief of pulmonary and critical care medicine at Norwalk Hospital.”

LUNGevity Foundation, Thomas G. Labrecque Foundation Join Together to Raise Awareness and Funds for Lung Cancer Research
“LUNGevity Foundation, the nation's largest lung cancer-focused nonprofit, and Thomas G. Labrecque Foundation, a leading supporter of lung cancer research and awareness, have agreed to collaborate to drive funding for lung cancer research and elevate awareness about the nation's number one cancer killer.”

States urged to restore funding for anti-smoking programs
“Steve Panetta smoked for 34 years, the last 10 at a three-pack-a-day clip. He watched his father die from lung cancer and his stepfather struggle with emphysema. He tried quitting six times before a state-funded cessation program helped him beat the habit in 2002.”

There's a surgical app for that, thanks to Dr. Bender
“The first thing Dr. Edward Bender and his fellow physicians do when they gather to go over new lung cancer cases is pull out their iPhones.”

New drug helps patients survive lung cancer
“We all know there's a strong association between smoking and lung cancer, but some non-smokers get lung cancer, too, and it can be due to a genetic mutation. Now, researchers are taking a genetic approach to shrinking tumors and helping patients survive lung cancer.”

Wisconsin launches PET lung cancer trial
“The University of Wisconsin Carbone Cancer Center in Madison has enrolled the first patient in a Phase 1-2 PET imaging trial of I-124-CLR1404 (LIGHT, Novelos Therapeutics), a cancer-targeted PET imaging agent, in patients with advanced non-small cell lung cancer (NSCLC).”

Lung Cancer: Do you know what symptoms to look out for?
“Do you know the warning signs for lung cancer? That was the topic of Tuesday’s “Facebook Story of the Day”.”

Week Ending February 19, 2012

FDA warning: Counterfeit version of cancer drug Avastin circulating
“Some cancer patients may not get proper treatment because a counterfeit version of the drug sold as Avastin 400mg/16mi has been purchased by as many as 19 medical practices in the United States, FDA warned Wednesday.”

Here Now - Lung cancer survivor still battling disease's stigma
“Taylor Bell faced a dilemma Wednesday morning as she pondered that night's big basketball game.”

LUNGevity and GRACE Present Seminar on Molecular Markers in Advanced Non-Small Cell Lung Cancer
“LUNGevity Foundation, the nation's largest lung cancer-focused nonprofit, in partnership with GRACE, continues its 2012 thought leader webinar series with "Molecular Markers in Advanced Non-Small Cell Lung Cancer: Who to Test and What to Test For." The webinar, taking place Wednesday, February 22, from 6:30 p.m. EST to 8:30 p.m. EST, will bring together four experts from different clinical settings to address the use of molecular testing in advanced non-small cell lung cancer.”

UC-Davis Cancer Center designing patient-specific treatments
“The scan, Dr. David Gandara said, looked really good. Romeo Topacio nodded. He has stage four lung cancer - the deadliest of cancers - and for a moment he sat quietly, taking in the doctor's words.”

High-Speed DNA Scans Help Most Lung Cancer Patients, Study Finds
“More than half of lung and colon cancer patients may benefit from high-speed tests that detect DNA flaws doctors can target with existing medicines, a study found.”

Cancer drug shortages hit close to home
“The shortage of popular cancer drugs continues to plague people not just here in the Panhandle, but across the nation.”

Most cancer patients get end-of-life care talks late
“Nearly three-quarters of patients with stage IV lung or colorectal cancer have end-of-life care discussions with physicians, but most of those talks come later than they should, said a study of nearly 2,200 patients published Feb. 7 in Annals of Internal Medicine.” (www.annals.org/content/156/3/204.abstract).

New Drug Target Found for Lung Cancer
ScienceDaily — “Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies.”

Breath test detects signs of lung cancer
Device could make early diagnosis easier

“A simple breath test could someday help doctors determine if a patient has lung cancer.”

New Lung Cancer Therapy
“It’s the number one cancer killer in America. We all know smoking causes it, but if you’ve never had a cigarette, a mutation in your genes could lead to lung cancer.”

Push for cancer screening of smokers
HEALTH experts are calling for screening of smokers for lung cancer, much the same way women are screened for breast cancer.

“They want Australia to investigate the health and economic benefits of screening smokers for lung cancer, our biggest cancer killer.”

Women and Lung Cancer: Time to Turn the Tide “There will be more than 220,000 people diagnosed with lung cancer in 2011. They will be our brothers, sisters, grandparents, co-workers, closest friends. They will be our parents.”

Week Ending February 12, 2012

U-M Cancer Center hosts online chat to answer questions about lung cancer
Chat participants can ask questions of U-M lung cancer doctor

“The University of Michigan wants to make sure everyone has the facts about lung cancer, a disease that kills more people each year than breast, colon and prostate cancers combined.On Feb. 16, U-M’s Comprehensive Cancer Center will host an online chat with Gregory Kalemkerian, M.D., director of the U-M Multidisciplinary Lung Cancer Clinic, to answer questions about the disease.”

High-Speed DNA Scans Help Most Lung Cancer Patients, Study Finds
“More than half of lung and colon cancer patients may benefit from high-speed tests that detect DNA flaws doctors can target with existing medicines, a study found.”

9/11 First Responders See Cancer Rates Triple
“New research has revealed that among the 12,000 police officers who responded to September 11th, 297 have been diagnosed with cancer-related disabilities, more than triple the rate before the attack.”

Collaboration to Study Disparities in Lung Cancer Treatments in Southern Illinois
“Southern Illinois University School of Medicine in Springfield, Southern Illinois Healthcare (SIH) Cancer Institute in Carbondale and the Illinois State Cancer Registry will collaborate on a two-year study that will explore disparities in the treatment of lung cancer in southern Illinois. SIH Cancer Institute is an affiliate of Simmons Cancer Institute at SIU.”

OSF’s new lung cancer clinic speeds up treatment
PEORIA — “Dr. James McGee is not sure why lung cancer rates are so high in Peoria County.”

Murrieta Firefighter To Tackle Work Following Cancer Treatment
“Firefighter/paramedic Dean Hale, 43, in January was declared cancer free, following treatment with a new drug that targeted his specific type of disease.”

Senator seeks notification on drugs' unavailability
Brown, cancer patient, doctor speak in Toledo

“Joanne Schwartzberg once was a clinical nurse at what was then the Medical College of Ohio Hospital, but now she's a patient, receiving chemotherapy for lung cancer.”

Potential therapeutic target for tobacco-related lung cancers identified
“Researchers have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers.”

Lung Cancer Alliance Announces National Framework for Lung Cancer Screening Excellence; Thousands of Lives at Stake
“Today, Lung Cancer Alliance (LCA) moved lung cancer screening to a national platform by announcing a Framework for Lung Cancer Screening Excellence which includes a bill of rights for the at-risk public and guiding principles for lung cancer screening sites.”

Cancer Patient Knows the Legacy She Wants to Leave
Wyandotte's Andrea Clary Vos is hosting her own estate sale so her family won't have to later. “Andrea Clary Vos may be battling stage four lung cancer, but she said she’s more determined than ever to make sure she leaves behind “less of a mess (and) more of a legacy.””

Week Ending February 5, 2012

Study highlights benefits of CT scans for heavy smokers
  “Jim Kindell was a chain smoker for 50 years. He had his first cigarette when he was about 11, and over the years he often burned through two packs of Camels a day. He tried quitting, but even hypnosis didn't work.”

Hospitals mine patient records in search of customers
“When the oversized postcard arrived last August from Provena St. Joseph Medical Center promoting a lung cancer screening for current or former smokers over 55, Steven Boyd wondered how the hospital had found him.”

Double Punch Urged for Lung Cancer
Lung cancer may respond to therapy targeting both JAK2 protein and STAT3 gene “Non-small cell lung cancer (NSCLC) is a tough one, but researchers have found a new target for treating this disease. When added to other therapies, the combination might just deliver a knock-out punch.”

New research confirms need for lung cancer testing
“Different kinds of lung cancer behave in different ways, suggesting they are fundamentally different diseases. According to a University of Colorado Cancer Center study published in Cancer, the official journal of the American Cancer Society, different subgroups of non-small cell lung cancer (NSCLC) show distinct patterns of spread in the body.”

Scientists demonstrate effective new 'biopsy in a blood test' to detect cancer
“Scripps Research Institute biophysicist Peter Kuhn and colleagues have captured images of tumor cells circulating in the blood stream, such as this cluster of lung tumor cells (in red-blue) shown interacting with normal blood cells (green-blue) recovered from a blood sample of patient with lung cancer. Credit: Image courtesy of the Kuhn lab, the Scripps Research Institute.”

Idaho Researcher Works to Create New Lung Cancer Test
“More people die from lung cancer each year, than any other cancer.  That’s according to the Centers for Disease Control and Prevention.  A Boise State University researcher wants to change that by developing an easy and inexpensive test for lung cancer.”

Wellness after cancer: Stanford opens clinic to address survivors’ needs
“Someone in my family survived lung cancer six years ago. The treatment didn’t include radiation or chemotherapy, and the tumor was removed neatly by an excellent surgeon. But the surgery scar still interferes with his normal muscle function, and the possibility that the cancer might come back is part of our family’s collective consciousness – and worry.”

Massachusetts General study defines a new genetic subtype of lung cancer
“A report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S. The researchers show that ROS1-driven tumors can be treated with crizotinib, which also inhibits the growth of tumors driven by an oncogene called ALK, and describe the remarkable response of one patient to crizotinib treatment.”


Week Ending January 29, 2012

New lung cancer test predicts survival
PARIS, Jan 28 — “Clinical trials in the United States and China have shown that a new gene-based test for patients with lung cancer beats standard methods in predicting survival, researchers reported yesterday.”

Powerful New Weapon in Fight Against Lung Cancer
“A study by the National Cancer Institute reveals encouraging news about the use of low dose CT lung screenings in early stage diagnosis of lung cancer.”

N.J. oncology network promises benefits for patients
“A statewide group of 76 oncologists have consolidated their practices into a new oncology network they said will lower costs and pool resources for more than one-third of New Jersey’s cancer patients.”

Comprehensive Lung Nodule Program at Cabell Huntington Hospital now offers low-cost screening for lung cancer
HUNTINGTON, WV – “The lung specialists at the Comprehensive Lung Nodule Program at Cabell Huntington Hospital and the Edwards Comprehensive Cancer Center are now offering a low-cost and potentially life-saving opportunity for certain people to be screened for early detection of lung cancer.”

'Desperate Housewives' Kathryn Joosten talks Lung Cancer, and how to fight back
“The end is near for both ABC's "Desperate Housewives" and the gossipy neighbor, Mrs. McClusky, played by Emmy award winning actress, Kathryn Joosten.”

AJR: Algorithm reduces benign lung biopsy rate
“When following a stringent diagnostic protocol in CT lung cancer screening, few biopsies will be recommended and performed on benign nodules, which should alleviate at least some concerns that low-dose CT screening produces a high false-positive rate, according to a study published in the February issue of the American Journal of Roentgenology.”

Elevated Rate of Lung Cancer Among Carolina Textile Workers Exposed to Asbestos, Study Says
“Researchers report that textile workers in North Carolina and South Carolina who were exposed to asbestos had significantly increased incidence of lung cancer. Asbestos, a mineral fiber used in thousands of products from building materials to textiles, is associated with serious respiratory diseases including asbestosis, a scarring of the lung, lung cancer and mesothelioma, a cancer of the lining of the lung and abdomen.”

Irish scientists make massive cancer breakthrough
Irish scientists have made a massive breakthrough in lung cancer research and the best thing about this breakthrough? It could help to stop the spread of this deadly disease.

“The Irish Daily Mirror reports that a study carried out at St James’s Hospital in Dublin has been hailed as a huge step forward and should lead to the development of new ways of treating the disease in the future.”

Week Ending January 22, 2012

Video Assisted Thoracic Surgery (VATS) for Stage 1 Lung Cancer
“Surgery for early stage lung cancer offers the chance for a cure, yet removing a lobe of a lung is a very major surgery.”

Medical debt puts more at risk
“Frances Giordano found out she had lung cancer in June. After that, the bad news just kept coming. Frances Giordano, 59, of Dumont is battling lung cancer, the loss of a job due to her illness and staggering medical bills.”

Summa Western Reserve offers free lung screenings Jan. 28
Cuyahoga Falls, OH – “There is a new tool in physicians' arsenal for the early detection of lung cancer and the city's Summa Western Reserve Hospital has it.”

Retiring Professor Elaine Rankin hails progress in lung cancer care
Tayside can boast one of the best centres for lung cancer treatment in the UK, a professor said this week.

“Elaine Rankin, consultant and professor of medical oncology, was speaking on Thursday as she retired from NHS Tayside after 13 years' service.”

Contribution of cell blocks obtained through endobronchial ultrasound-guided transbronchial needle aspiration to the diagnosis of lung cancer
“Conventional smears of samples obtained by endobronchial ultrasound with real-time transbronchial needle aspiration (EBUS-TBNA) have proven useful in lung cancer staging, but the value of additional information from cell-block processing of EBUS-TBNA samples has only been marginally investigated. This study focussed on the contribution of cell block analysis to the diagnostic yield in lung cancer.”

Radon Gas and Lung Cancer
“When it comes to reducing your cancer risk, one important step could be right under your nose, or below your feet. Getting your home tested for radon can help protect you and your family from a key cause of lung cancer.”

Lung cancer specialist receives thanks from grateful patients
Ross Camidge’s work produces thousands of dollars of donations

“University of Colorado Hospital’s President and CEO Bruce Schroffel made a surprise appearance at a meeting of the University of Colorado Cancer Center’s Tumor Board Jan. 9 to honor medical oncologist Ross Camidge, MD, PhD, for his service to patients.”

Study examines drug resistance in ALK positive lung cancer
AURORA, Colo. – “Scientists from the University of Colorado Cancer Center have once again advanced the treatment of a specific kind of lung cancer. The team has documented how anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) becomes resistant to a drug targeting the abnormal protein in the cancer. It's the first time scientists have analyzed the frequency and type of drug resistance in ALK positive patients taking crizotinib.”

Nurse helps patients navigate care
“When Laurie Burrows was diagnosed with lung cancer last July, it was like falling off a cliff.”

Circulating Tumor Cells Predict Small-Cell Lung CA Prognosis
“The number of circulating tumor cells (CTCs) and the change in CTC number after one cycle of chemotherapy predict prognosis in patients with small-cell lung cancer, according to a study published online Jan. 17 in the Journal of Clinical Oncology.”

Week Ending January 16, 2012

Radon kits are available
“Gov. Mark Dayton has issued a proclamation declaring January 2012 Radon Action Month in Minnesota to promote awareness of this important health issue. Freeborn County Public Health will offer free radon test kits to homeowners in Freeborn County in order to encourage homeowners to test.”

Residents encouraged to test homes for radon with free kits
LAS VEGAS (FOX5) – “Nevada residents may be surprised to know that the leading cause of lung cancer for nonsmokers is radon.”

Guest Column: Lung-Cancer Survivor Aims to Raise Awareness in the State College Area
“It is truly sad and disappointing to dwell on the negative and hope to gain recognition and position by criticizing, running down, calling for the defeat of an opponent rather then presenting ideas, abilities to improve, make a situation better by what one has to offer that is helpful and positive.”

Tests Might Someday Help Spot Early Lung Cancer
(HealthDay News) – “Lung cancer is the leading cancer killer in the world, and only about 15 percent of cases are diagnosed at an early stage, when it's most treatable.”

Irish Cancer Society concerned over rising lung cancer rates in women
“At the launch of the Irish Cancer Society’s Lung Cancer Awareness campaign 2012, the society has expressed concern at a recent report which shows lung cancer has overtaken breast cancer as the biggest cause of cancer death in women in Ireland for the first time. This year the society is encouraging everyone to Look After Your Lungs, know how best to prevent lung cancer, know the signs and symptoms and if you are concerned, go to your GP.”

Pfizer signs biomarker deal for personalised lung cancer drug
“Pfizer has signed a three-way deal with Roche subsidiary Ventana Medical Systems and Cell Signalling Technology to develop a companion diagnostic for its recently-approved lung cancer drug Xalkori.”

New Study Helps Predict Which Lung Cancer Drugs are Most Likely to Work
“Researchers at Johns Hopkins have shown that DNA changes in a gene that drives the growth of a form of lung cancer can make the cancer’s cells resistant to cancer drugs. The findings show that some classes of drugs won’t work, and certain types of so-called kinase inhibitors like erlotinib—may be the most effective at treating non-small cell lung cancers with those DNA changes. Some kinase inhibitors block a protein known as EGFR from directing cells to multiply.”

Week Ending January 9, 2012

Lung cancer conference to focus on new diagnostic techniques, potential treatments
SAN DIEGO – “Lung cancer is the most commonly diagnosed cancer in the United States and often the most fatal unless caught early, but scientists are working on ways to improve their understanding of the disease.

Several hundred of scientists will gather in San Diego at the San Diego Marriott Marquis & Marina during Jan. 8-11, 2012, for the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine.”

‘Lung cancer gene’ pinned
“Singapore scientists, headed by Dr Bing Lim, Associate Director of Cancer Stem Cell Biology at the Genome Institute of Singapore (GIS), a research institute under the umbrella of the Agency for Science, Technology and Research (A*STAR), and Dr Elaine Lim, medical oncologist affiliated with Tan Tock Seng Hospital (TTSH) and National Cancer Centre Singapore (NCCS), have, for the first time, identified a gene responsible for lung cancer. The finding, reported in the advanced online issue of Cell on 5 January 2012, is a huge step towards finding a cure for the disease.”

Custirsen Shows Promise For Advanced Non-small Cell Lung Cancer
“Data assessing custirsen (OGX-011/TV-1011), an investigational compound, in individuals with advanced non-small cell lung cancer (NSCLC) were published online in the January 2012 issue of the Journal of Thoracic Oncology, OncoGenex Pharmaceuticals, Inc. announced January 4th.”

VisionGate Uses $2.6 Million NIH Grant to Achieve Full Automation of Cell-CT(TM) 3D Imaging System for Early Diagnosis of Cancer
“VisionGate, Inc., a company developing a revolutionary non-invasive test for the early detection of lung cancer and other applications, today reported that it has achieved full automation of its Cell-CT(TM) system, a proprietary imaging platform that generates high-resolution 3D biosignatures from intact cells.”

Oregonians are Urged to Test Their Home for Radon, a Leading Cause of Lung Cancer in the US
“You can’t see it, smell it or taste it, but radon could be in your home at dangerous levels. The Oregon Radon Program is working with the United States Environmental Protection Agency (EPA) in a nationwide campaign to educate people about the dangers of radon. January is National Radon Action Month.”

Chris Draft, NFL Retiree, Buries Wife One Month After Wedding, Sheds Light On Lung Cancer Among Non-Smokers
“Lakeasha Monique Rutledge Draft "courageously faced lung cancer, showing us all with every breath that we all need to hold onto life and love with both hands for as long as we can" her husband and former NFL star Chris Draft wrote on his foundation's website last week, honoring his wife who died from lung cancer on December 27, just one month after the couple wed.”

Week Ending January 1, 2012

ASCO Picks Top Advances in Cancer Treatment
“Advances in screening and prevention, treatments for refractory cancers, and ways to reduce cancer recurrence were part and parcel of the progress made against the disease in 2011, according to the American Society of Clinical Oncology.”

Scientists outline new guidelines for future of lung cancer screening
“The International Association for the Study of Lung Cancer Task Force, chaired by Professor John Field from the University’s Cancer Research Centre, has identified six areas of research to further progress investigations into the feasibility of lung cancer screening programmes at hospitals around the world.”

Nutrition and Lung Cancer
Lessons from the Differing Effects of Foods and Supplements

“In this issue of the Journal (pp. 524–530), Slatore and coworkers report findings on the association between nutritional supplement use and lung cancer risk using information from a cohort of 77,721 adults in Washington State.”

Biomarker Identifies Patients With Advanced Lung Cancer Who Will Gain Most From Add-On Cetuximab
“Investigators reported that high tumor epidermal growth factor receptor (EGFR) expression is a predictive biomarker that defines patients with advanced non–small cell lung cancer (NSCLC) who are most likely to derive a survival benefit from the addition of cetuximab to platinum-based, first-line chemotherapy.”

CHEST Foundation awards $100,000 for development of blood test for lung cancer
“Lung cancer takes a heavy toll, contributing to more cancer deaths in the United States each year than breast, prostate and colon cancers combined. Contributing to this poor prognosis is the fact that lung cancer often goes undetected until the disease has reached an advanced and more difficult-to-treat stage.”

State law will let tenants get info on radon levels
SPRINGFIELD, IL — “A new state law will allow tenants to access information on whether a home has been tested for radon, a naturally-occurring radioactive gas known to cause lung cancer. The law takes effect Sunday.”

Axelar initiates a Phase II clinical study with AXL1717 for the treatment of non-small cell lung cancer
“AXL1717 is the first targeted oral small-molecule Insulin-like Growth Factor 1 (IGF-1) receptor inhibitor clinically tested which does not affect the closely-related insulin receptor. In the recently completed Phase I/II study, AXL1717 demonstrated a good safety profile and signs that suggest clinical benefit were observed in some patients with NSCLC.”

Court Rules NYPD First Responder Frank Macri’s Fatal Cancer Caused by 9/11
“The New York Appellate Division of State Supreme Court ruled in favor of Nilda Macri, who has been in court for the last four years, trying to collect line-of-duty death benefits after her husband, NYPD Officer and September 11th first responder Frank Macri, died from lung cancer that he developed after working at Ground Zero for two months.”

Sequencing Study Unearths Gene Fusion in Lung Cancer from Never-Smoker
“A gene fusion identified in DNA and RNA sequences from a never-smoker lung cancer patient may act as a driver in a subset of lung cancer cases, a new study suggests.”

Last Updated on Monday, 07 January 2013 23:27
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